IFN-γ/Interferon gamma Antibody (F12): sc-52681
- IFN-γ/Interferon gamma Antibody (F12) is a mouse monoclonal IgG1 provided at 100 µg/ml
- recommended for detection of both recombinant and native IFN-γ of human origin by WB, IP and IF; non cross-reactive with other cytokines or rodent interferons
- See IFN-γ/Interferon gamma (E-10): sc-373727 for IFN-γ/Interferon gamma antibody conjugates, including AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 and 790.
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for IFN-γ/Interferon gamma Antibody (F12). This work is in progress.
IFN-γ Antibody (F12) is a mouse monoclonal IgG1 antibody that detects Interferon (IFN)-γ in human samples through applications such as western blotting (WB), immunoprecipitation (IP), and immunofluorescence (IF). IFN-γ plays a crucial role in the immune response, acting as an antiviral and antiparasitic agent produced by activated CD4+/CD8+ lymphocytes and natural killer cells. IFN-γ production is stimulated by various factors, including antigens, mitogens, and alloantigens, and is essential for modulating T cell growth and differentiation while inhibiting B cell proliferation. The active form of IFN-γ is a homodimer, with each subunit comprising six helices. This dimeric configuration is stabilized by non-covalent interactions at the interface of the helices, which is vital for biological activity. The IFN-γ precursor consists of 166 amino acids, including a 23 amino acid secretory sequence, and multiple forms exist due to variable glycosylation and the ability to form dimers and tetramers under non-denaturing conditions, highlighting the complexity of regulation and function. Anti-IFN-γ antibody (F12) is an invaluable tool for researchers studying immune responses and the intricate mechanisms of cytokine signaling.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
IFN-γ/Interferon gamma Antibody (F12) | sc-52681 | 100 µg/ml | $322.00 |