ICAM-1/CD54 Antibody (TLD-3H7A): sc-53527
- ICAM-1/CD54 Antibody (TLD-3H7A) is a mouse monoclonal IgG1 κ, cited in 1 publications, provided at 200 µg/ml
- raised against cultured microglial cells of rat origin
- recommended for detection of ICAM-1 of mouse and rat origin by WB, IF, IHC(P) and FCM
- available conjugated to either phycoerythrin or FITC for IF, IHC(P) and FCM
- See ICAM-1/CD54 (G-5): sc-8439 for ICAM-1/CD54 antibody conjugates, including AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 and 790.
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for ICAM-1/CD54 Antibody (TLD-3H7A). This work is in progress.
ICAM-1 Antibody (TLD-3H7A) is a mouse monoclonal IgG1 kappa light chain antibody raised against cultured microglial cells of rat origin, demonstrating reactivity with mouse and rat species. Anti-ICAM-1 antibody (TLD-3H7A) is suitable for applications such as western blotting (WB), immunoprecipitation (IP), and flow cytometry (FCM). ICAM-1, also known as CD54 or intercellular adhesion molecule-1, is a cell surface glycoprotein belonging to the immunoglobulin superfamily. ICAM-1 plays a crucial role in mediating cell-cell adhesion during immune responses by interacting with leukocyte integrins like LFA-1 (CD11a/CD18) and Mac-1 (CD11b/CD18). ICAM-1 undergoes post-translational modifications, including N-linked glycosylation and phosphorylation, which are important for stability, localization, and function. These modifications can influence ICAM-1′s ability to mediate adhesion and signal transduction, affecting immune responses and inflammation. Altered expression or modification of ICAM-1 is associated with various pathological conditions, such as autoimmune diseases, cardiovascular disorders, and cancer metastasis. Understanding post-translational modifications of ICAM-1 is essential for research into inflammatory processes and potential therapeutic interventions. Anti-ICAM-1 antibody (TLD-3H7A) provides a valuable tool for researchers studying ICAM-1 function and regulation in physiological and pathological contexts.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
ICAM-1/CD54 Antibody (TLD-3H7A) | sc-53527 | 200 µg/ml | $316.00 | |||
ICAM-1/CD54 Antibody (TLD-3H7A) FITC | sc-53527 FITC | 200 µg/ml | $330.00 | |||
ICAM-1/CD54 Antibody (TLD-3H7A) PE | sc-53527 PE | 200 µg/ml | $343.00 |