Hydroxy Itraconazole-d5 (CAS 1217524-77-0)
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Hydroxy Itraconazole-d5 is a deuterated derivative of hydroxy itraconazole, designed for use in scientific research, particularly in the field of mass spectrometry and analytical chemistry. By incorporating deuterium atoms in place of hydrogen, this compound offers a distinctive mass shift that facilitates its identification and quantification in complex biological matrices, making it an invaluable tool for pharmacokinetic studies, drug metabolism research, and the elucidation of metabolic pathways. Its mechanism of action is akin to its non-deuterated counterpart, interacting with specific targets to inhibit the synthesis of ergosterol, a critical component of fungal cell membranes, thus serving as a reference standard in studies investigating the metabolism and mechanism of action of itraconazole and its metabolites. Hydroxy Itraconazole-d5′s unique properties enhance the accuracy and reliability of analytical methods, contributing to advancements in the understanding of chemical behavior in biological systems.
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Hydroxy Itraconazole-d5 (CAS 1217524-77-0) References
- Immobilization of protein-coated drug nanoparticles in nanofibrillar cellulose matrices--enhanced stability and release. | Valo, H., et al. 2011. J Control Release. 156: 390-7. PMID: 21802462
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Hydroxy Itraconazole-d5, 1 mg | sc-280798 | 1 mg | $889.00 | |||
Hydroxy Itraconazole-d5, 10 mg | sc-280798A | 10 mg | $4687.00 |