Date published: 2025-11-21

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Hydrocortisone 21-hemisuccinate sodium salt (CAS 125-04-2)

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Alternate Names:
Hydrocortisone 21-hemisuccinate sodium salt is also known as Cortisol 21-hemisuccinate.
Application:
Hydrocortisone 21-hemisuccinate sodium salt is useful for epithelial and endothelial adherent cell culture applications.
CAS Number:
125-04-2
Purity:
≥98%
Molecular Weight:
484.51
Molecular Formula:
C25H33O8•Na
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Hydrocortisone 21-hemisuccinate sodium salt is a water-soluble form of the endogenous hormone cortisol. It is useful for epithelial and endothelial adherent cell culture applications. Since It can bind to glucocorticoid receptors, the transcription of anti-inflammatory nand immunosuppressive mediators can be initiated. Hydrocortisone 21-hemisuccinate sodium salt will also inhibit proinflammatory cytokine activity.


Hydrocortisone 21-hemisuccinate sodium salt (CAS 125-04-2) References

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  2. Serum Free Production of Three-dimensional Human Hepatospheres from Pluripotent Stem Cells.  |  Lucendo-Villarin, B., et al. 2019. J Vis Exp.. PMID: 31380852
  3. Cellular uptake and toxicity of gold nanoparticles on two distinct hepatic cell models.  |  Enea, M., et al. 2021. Toxicol In Vitro. 70: 105046. PMID: 33147519
  4. Differentiation of induced pluripotent stem cells to hepatocyte-like cells on cellulose nanofibril substrate.  |  Poorna, MR., et al. 2021. Colloids Surf B Biointerfaces. 198: 111466. PMID: 33243549
  5. Characterisation of Drug Delivery Efficacy Using Microstructure-Assisted Application of a Range of APIs.  |  Rahbari, R., et al. 2020. Pharmaceutics. 12: PMID: 33333795
  6. Mathematical modelling of oxygen gradients in stem cell-derived liver tissue.  |  Leedale, JA., et al. 2021. PLoS One. 16: e0244070. PMID: 33556073
  7. Modeling human hepatic steatosis in pluripotent stem cell-derived hepatocytes.  |  Sinton, MC., et al. 2021. STAR Protoc. 2: 100493. PMID: 33997813
  8. Protocol for automated production of human stem cell derived liver spheres.  |  Meseguer-Ripolles, J., et al. 2021. STAR Protoc. 2: 100502. PMID: 33997816
  9. An Efficient Method for Directed Hepatocyte-Like Cell Induction from Human Embryonic Stem Cells.  |  Zhou, Q., et al. 2021. J Vis Exp.. PMID: 34028444
  10. Comparative Anti-Inflammatory Effects of Salix Cortex Extracts and Acetylsalicylic Acid in SARS-CoV-2 Peptide and LPS-Activated Human In Vitro Systems.  |  Le, NPK., et al. 2021. Int J Mol Sci. 22: PMID: 34201817
  11. Generation of a human iPSC line CIBi010-A with a reporter for ASGR1 using CRISPR/Cas9.  |  Fu, J., et al. 2022. Stem Cell Res. 62: 102800. PMID: 35561459
  12. In Vitro Toxicological Profile of Labetalol-Folic Acid/Folate Co-Administration in H9c2(2-1) and HepaRG Cells.  |  Rednic, R., et al. 2022. Medicina (Kaunas). 58: PMID: 35744047
  13. Universal Markers for hiPSCs Residue Detection.  |  Shi, H., et al. 2022. Front Biosci (Landmark Ed). 27: 239. PMID: 36042179
  14. Eugenol Induces Apoptosis in Tongue Squamous Carcinoma Cells by Mediating the Expression of Bcl-2 Family.  |  Surducan, DA., et al. 2022. Life (Basel). 13: PMID: 36675971

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Hydrocortisone 21-hemisuccinate sodium salt, 100 mg

sc-250130
100 mg
$42.00

Hydrocortisone 21-hemisuccinate sodium salt, 1 g

sc-250130A
1 g
$316.00