hnRNP A2/B1 Antibody (B-8): sc-393726
- hnRNP A2/B1 Antibody (B-8) is a mouse monoclonal IgG3 κ provided at 200 µg/ml
- specific for an epitope mapping between amino acids 226-255 within an internal region of hnRNP A2/B1 of human origin
- recommended for detection of hnRNP A2/B1 of mouse, rat and human origin by WB, IP, IF and ELISA
- See hnRNP A2/B1 (B-7): sc-374053 for hnRNP A2/B1 antibody conjugates, including AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 and 790.
- m-IgG3 BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for hnRNP A2/B1 Antibody (B-8) for WB applications. These reagents are now offered in bundles with hnRNP A2/B1 Antibody (B-8) (see ordering information below).
hnRNP A2/B1 Antibody (B-8) is a mouse monoclonal IgG3 antibody that detects hnRNP A2/B1 in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). hnRNP A2/B1 plays a crucial role in pre-mRNA processing and is essential for proper mRNA splicing, which is vital for gene expression and cellular function. hnRNP A2/B1 is primarily located in the nucleus, where hnRNP A2/B1 interacts with pre-mRNA and various splicing factors, influencing splice site selection and ensuring mature mRNA production. The ability of hnRNP A2/B1 to shuttle between the nucleus and cytoplasm enables participation in both mRNA processing and transport, highlighting hnRNP A2/B1′s importance in maintaining dynamic gene expression regulation. hnRNP A2/B1 forms complexes with other hnRNP proteins, contributing to spliceosome assembly, which is critical for accurate pre-mRNA splicing. The versatility of hnRNP A2/B1 in these processes underscores hnRNP A2/B1′s significance in cellular biology and potential as a target for research into gene regulation and related diseases.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
hnRNP A2/B1 Antibody (B-8) | sc-393726 | 200 µg/ml | $316.00 | |||
hnRNP A2/B1 Antibody (B-8): m-IgGκ BP-HRP Bundle | sc-535875 | 200 µg Ab; 40 µg BP | $354.00 | |||
hnRNP A2/B1 Antibody (B-8): m-IgG3 BP-HRP Bundle | sc-550314 | 200 µg Ab; 40 µg BP | $354.00 | |||
hnRNP A2/B1 (B-8) Neutralizing Peptide | sc-393726 P | 100 µg/0.5 ml | $68.00 |