Date published: 2025-10-15

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HIV-1 p24 Antibody (2N34): sc-130536

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Datasheets
  • HIV-1 p24 Antibody (2N34) is a mouse monoclonal IgG1 provided at 100 µg/ml
  • raised against recombinant p24 protein of HIV-1 (B subtype) origin with epitope mapping to amino acids 74-84
  • recommended for detection of Gag p24 of HIV-1 origin by WB
  • See HIV-1 p24 (24-4): sc-69728 for HIV-1 p24 antibody conjugates, including AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 and 790.
  • At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for HIV-1 p24 Antibody (2N34). This work is in progress.

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    HIV-1 p24 Antibody (2N34) is a mouse monoclonal IgG1 antibody that detects p24 protein of HIV-1 by western blotting (WB). p24 (2N34) monoclonal antibody plays a crucial role in the study of human immunodeficiency virus (HIV), particularly in understanding viral structural components. p24 protein forms the viral capsid, which protects viral RNA and enzymes during infection. This capsid structure facilitates viral genome delivery into host cells and plays a significant role in viral assembly and maturation. By targeting p24, researchers can gain insights into viral life cycles and mechanisms of HIV pathogenesis, vital for developing effective therapeutic strategies and vaccines against HIV/AIDS. anti-p24 antibody (2N34) specificity for HIV-1 strain enhances utility in various research applications, making p24 (2N34) monoclonal antibody an indispensable tool for scientists studying viral infections and immune responses.

    For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.

    Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA

    LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences

    HIV-1 p24 Antibody (2N34) References:

    1. Maturation-induced conformational changes of HIV-1 capsid protein and identification of two high affinity sites for cyclophilins in the C-terminal domain.  |  Endrich, MM., et al. 1999. J Biol Chem. 274: 5326-32. PMID: 10026140
    2. Near-full-length genome sequencing of divergent African HIV type 1 subtype F viruses leads to the identification of a new HIV type 1 subtype designated K.  |  Triques, K., et al. 2000. AIDS Res Hum Retroviruses. 16: 139-51. PMID: 10659053
    3. Human immunodeficiency virus type 1 neutralization measured by flow cytometric quantitation of single-round infection of primary human T cells.  |  Mascola, JR., et al. 2002. J Virol. 76: 4810-21. PMID: 11967298
    4. Mice infection with HIV-1: a new mouse model for HIV-1 in vivo research.  |  Filice, G., et al. 1992. Microbiologica. 15: 167-75. PMID: 1602987
    5. Inhibition of HIV-1 replication by siRNA targeting conserved regions of gag/pol.  |  Morris, KV., et al. 2005. RNA Biol. 2: 17-20. PMID: 17132935
    6. Two immunomodulators, curcumin and sulfasalazine, enhance IDV antiretroviral activity in HIV-1 persistently infected cells.  |  Riva, DA., et al. 2008. Arch Virol. 153: 561-5. PMID: 18175040
    7. Low-level HIV infection of hepatocytes.  |  Kong, L., et al. 2012. Virol J. 9: 157. PMID: 22877244
    8. [A novel SELEX method for screening of HIV-1 P24 antigen].  |  Zhan, SB., et al. 2013. Zhonghua Shi Yan He Lin Chuang Bing Du Xue Za Zhi. 27: 218-20. PMID: 24319963
    9. Purified human breast milk MUC1 and MUC4 inhibit human immunodeficiency virus.  |  Mthembu, Y., et al. 2014. Neonatology. 105: 211-7. PMID: 24503884
    10. Infection, apoptosis, and killing of mature human eosinophils by human immunodeficiency virus-1.  |  Weller, PF., et al. 1995. Am J Respir Cell Mol Biol. 13: 610-20. PMID: 7576698

    Ordering Information

    Product NameCatalog #UNITPriceQtyFAVORITES

    HIV-1 p24 Antibody (2N34)

    sc-130536
    100 µg/ml
    $316.00