Date published: 2025-10-14

1-800-457-3801

SCBT Portrait Logo
Seach Input

Hexaethylene glycol monodecyl ether (CAS 5168-89-8)

0.0(0)
Write a reviewAsk a question

Alternate Names:
Decylhexaglycol
Application:
Hexaethylene glycol monodecyl ether is a nonionic surfactant useful for proteomics research
CAS Number:
5168-89-8
Molecular Weight:
422.60
Molecular Formula:
C22H46O7
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

QUICK LINKS

Hexaethylene glycol monodecyl ether is a nonionic surfactant known for its molecular structure, which combines a hydrophobic decyl tail with a hydrophilic chain of six ethylene glycol units. This amphiphilic nature enables it to effectively reduce surface and interfacial tensions, facilitating the stable mixing of aqueous and organic phases. In research, it is particularly valued for its role in the synthesis and stabilization of nanoparticles; its ability to prevent particle aggregation is crucial for maintaining consistent size and distribution, which is essential for the reproducibility and functionality of nanotechnological applications. Additionally, hexaethylene glycol monodecyl ether is used in studying biological membranes, where it aids in the solubilization and analysis of membrane proteins and lipids without disrupting their native states. This makes it an indispensable tool in areas like materials science, where it enhances the performance and application of advanced materials by modifying their surface characteristics, thereby contributing significantly to scientific advancements in both theoretical and applied research domains.


Hexaethylene glycol monodecyl ether (CAS 5168-89-8) References

  1. Solubilization and characterization of the anthrax toxin pore in detergent micelles.  |  Vernier, G., et al. 2009. Protein Sci. 18: 1882-95. PMID: 19609933
  2. A high-throughput differential filtration assay to screen and select detergents for membrane proteins.  |  Vergis, JM., et al. 2010. Anal Biochem. 407: 1-11. PMID: 20667442
  3. Crystal structure of the Vibrio cholerae cytolysin heptamer reveals common features among disparate pore-forming toxins.  |  De, S. and Olson, R. 2011. Proc Natl Acad Sci U S A. 108: 7385-90. PMID: 21502531
  4. The variable detergent sensitivity of proteases that are utilized for recombinant protein affinity tag removal.  |  Vergis, JM. and Wiener, MC. 2011. Protein Expr Purif. 78: 139-42. PMID: 21539919
  5. Molecular architecture and functional analysis of NetB, a pore-forming toxin from Clostridium perfringens.  |  Savva, CG., et al. 2013. J Biol Chem. 288: 3512-22. PMID: 23239883
  6. Identification of a key residue for oligomerisation and pore-formation of Clostridium perfringens NetB.  |  Fernandes da Costa, SP., et al. 2014. Toxins (Basel). 6: 1049-61. PMID: 24625763
  7. High-throughput stability screening for detergent-solubilized membrane proteins.  |  Kotov, V., et al. 2019. Sci Rep. 9: 10379. PMID: 31316088
  8. Three-dimensional structure of human cyclooxygenase (hCOX)-1.  |  Miciaccia, M., et al. 2021. Sci Rep. 11: 4312. PMID: 33619313
  9. Expression and purification of phage T7 ejection proteins for cryo-EM analysis.  |  Swanson, NA., et al. 2021. STAR Protoc. 2: 100960. PMID: 34825220
  10. Influence of Temperature and Concentration on the Self-Assembly of Nonionic CiEj Surfactants: A Light Scattering Study.  |  Kroll, P., et al. 2022. ACS Omega. 7: 7057-7065. PMID: 35252696

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Hexaethylene glycol monodecyl ether, 1 ml

sc-280771
1 ml
$147.00