H2-I/Ab Antibody (DaB2): sc-65383
- H2-I/Ab Antibody (DaB2) is a mouse monoclonal IgG1 provided at 100 µg/ml
- raised against C57B1 splenocytes of mouse origin
- recommended for detection of MHC class II I-Ab haplotype of mouse origin by IF and FCM
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for H2-I/Ab Antibody (DaB2). This work is in progress.
H2-I/Ab Antibody (DaB2) is a mouse monoclonal IgG1 antibody that detects H2-I in mouse samples through immunofluorescence (IF) and flow cytometry (FCM) applications. H2-I is a crucial component of the major histocompatibility complex (MHC) class II molecules, which play a vital role in the immune response by presenting processed antigens to CD4+ T cells. Anti-H2-I antibody (DaB2) enables research into interactions essential for T lymphocyte activation, key players in orchestrating the adaptive immune response. H2-I protein is primarily located on the surface of antigen-presenting cells, such as B cells, macrophages, and dendritic cells, where H2-I facilitates the recognition of foreign peptides. Proper functioning of H2-I is critical for the immune system′s ability to distinguish between self and non-self, thereby preventing autoimmune reactions and ensuring effective immune surveillance. Additionally, the polymorphic nature of H2-I allows for a diverse range of peptide presentation, enhancing the adaptability of the immune response to various pathogens. H2-I monoclonal antibody (DaB2) is an invaluable tool for researchers studying immune responses, antigen presentation, and the intricate mechanisms of T cell activation in mouse models.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
H2-I/Ab Antibody (DaB2) | sc-65383 | 100 µg/ml | $322.00 |