Guanabenz acetate is an α2A-AR adrenergic agonist and IGRS (imidazoline I2 binding site) selective ligand. Guanabenz acetate is an activator of alpha2B-AR (α2b-adrenergic receptor) and alpha2C-AR (α2c-adrenergic receptor).
1. Holmes, B., et al. 1983. Drugs. 26: 212-229. 2. Michel, M.C. and Insel, P.A. 1989. Trends Pharmacol Sci. 10: 342-344. 3. Evans, R.G. and Anderson, W.P. 1995. Br. J. Pharmacol. 116: 1557-1570.
Soluble in DMSO (75 mM), water (11 mg/ml at 25° C), alcohol (50 mg/ml at 25° C), chloroform (0.6 mg/ml at 25° C), and propylene glycol (100 mg/ml at 25° C).
Store at room temperature
192.5° C (dec.)
405.7° C at 760 mmHg (tautomer)
n20D ~1.65 (Predicted)
Plasmodium falciparum: IC50 = 3.16 µM
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
Download SDS (MSDS)
Certificate of Analysis
Adobe Acrobat Reader is required to reliably view, print and comment on PDF documents
bvseo_sdk, java_sdk, bvseo-3.2.0
CLOUD, getContent, 115ms
bvseo-msg: The resource to the URL or file is currently unavailable.;
Rated 5 out of
Inhibitor of eIF2α dephosphorylationEfficient for inhibiting eIF2α (α-subunit of eukaryotic initiation factor 2) dephosphorylation in the parasitic protist Toxoplasma.
Date published: 2017-09-05
Rated 5 out of
VieiraVieira, FG. et al. (PubMed 26288094) reported that Guanabenz treatment accelerated disease in a mutant SOD1 mouse model of ALS. -SCBT Publication Review
To place an order using RMB or to ship to mainland China, please visit www.scbio.cn