Date published: 2025-12-3

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Glyoxal trimer dihydrate (CAS 4405-13-4)

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Alternate Names:
Ethanedial trimer dihydrate; Hexahydro[1,4]dioxino[2,3-b]-1,4-dioxin-2,3,6,7-tetrol
Application:
Glyoxal trimer dihydrate is a glyoxal trimer used in the synthesis of various polycyclic compounds
CAS Number:
4405-13-4
Purity:
≥90%
Molecular Weight:
210.14
Molecular Formula:
C6H10O8
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Glyoxal trimer dihydrate is a chemical compound of interest in the field of polymer and materials science. Researchers study this compound for its potential role as a crosslinking agent due to its reactive aldehyde groups. The trimeric form of glyoxal, when hydrated, provides a model for understanding the behavior of glyoxal in aqueous environments, including its polymerization reactions and interactions with other organic molecules. In environmental chemistry, Glyoxal trimer dihydrate is investigated for its formation and stability under various conditions, which is relevant for understanding the fate of glyoxal in the atmosphere and its possible contribution to secondary organic aerosol formation. Additionally, this compound is used in analytical studies to develop methods for the detection and quantification of glyoxal and its oligomers in environmental samples, employing techniques such as chromatography and spectrometry.


Glyoxal trimer dihydrate (CAS 4405-13-4) References

  1. Regiospecific synthesis of 3-substituted imidazo[1,2-a]pyridines, imidazo[1,2-a]pyrimidines, and imidazo[1,2-c]pyrimidine.  |  Katritzky, AR., et al. 2003. J Org Chem. 68: 4935-7. PMID: 12790603
  2. Reaction of glyoxal with 2'-deoxyguanosine, 2'-deoxyadenosine, 2'-deoxycytidine, cytidine, thymidine, and calf thymus DNA: identification of DNA adducts.  |  Olsen, R., et al. 2005. Chem Res Toxicol. 18: 730-9. PMID: 15833033
  3. Secondary organic aerosol formation by glyoxal hydration and oligomer formation: humidity effects and equilibrium shifts during analysis.  |  Hastings, WP., et al. 2005. Environ Sci Technol. 39: 8728-35. PMID: 16323769
  4. Oligomer formation in evaporating aqueous glyoxal and methyl glyoxal solutions.  |  Loeffler, KW., et al. 2006. Environ Sci Technol. 40: 6318-23. PMID: 17120559
  5. Rate coefficients for the OH + HC(O)C(O)H (glyoxal) reaction between 210 and 390 K.  |  Feierabend, KJ., et al. 2008. J Phys Chem A. 112: 73-82. PMID: 18052049
  6. Secondary organic aerosol-forming reactions of glyoxal with amino acids.  |  De Haan, DO., et al. 2009. Environ Sci Technol. 43: 2818-24. PMID: 19475956
  7. HCO quantum yields in the photolysis of HC(O)C(O)H (glyoxal) between 290 and 420 nm.  |  Feierabend, KJ., et al. 2009. J Phys Chem A. 113: 7784-94. PMID: 19522522
  8. Convenient ultrasound-mediated synthesis of 1,4-diazabutadienes under solvent-free conditions.  |  He, JY., et al. 2011. Ultrason Sonochem. 18: 466-9. PMID: 20797893
  9. Glyoxal in aqueous ammonium sulfate solutions: products, kinetics and hydration effects.  |  Yu, G., et al. 2011. Environ Sci Technol. 45: 6336-42. PMID: 21721547
  10. Laboratory investigation on the role of organics in atmospheric nanoparticle growth.  |  Wang, L., et al. 2011. J Phys Chem A. 115: 8940-7. PMID: 21749081
  11. Raman spectroscopy of glyoxal oligomers in aqueous solutions.  |  Avzianova, E. and Brooks, SD. 2013. Spectrochim Acta A Mol Biomol Spectrosc. 101: 40-8. PMID: 23099158
  12. Heterogeneous chemistry of glyoxal on acidic solutions. An oligomerization pathway for secondary organic aerosol formation.  |  Gomez, ME., et al. 2015. J Phys Chem A. 119: 4457-63. PMID: 25369518
  13. Glyoxal measurement with a proton transfer reaction time of flight mass spectrometer (PTR-TOF-MS): characterization and calibration.  |  Stönner, C., et al. 2017. J Mass Spectrom. 52: 30-35. PMID: 27712005
  14. Large-scale synthesis of galeterone and lead next generation galeterone analog VNPP433-3β.  |  Purushottamachar, P., et al. 2022. Steroids. 185: 109062. PMID: 35690119
  15. The prebiotic synthesis and catalytic role of imidazoles and other condensing agents.  |  Oró, J., et al. 1984. Orig Life. 14: 237-42. PMID: 6462668

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Glyoxal trimer dihydrate, 100 mg

sc-252862E
100 mg
$26.00

Glyoxal trimer dihydrate, 1 g

sc-252862
1 g
$130.00

Glyoxal trimer dihydrate, 5 g

sc-252862A
5 g
$240.00

Glyoxal trimer dihydrate, 25 g

sc-252862B
25 g
$600.00

Glyoxal trimer dihydrate, 50 g

sc-252862C
50 g
$898.00

Glyoxal trimer dihydrate, 100 g

sc-252862D
100 g
$1699.00