GLP-1 Antibody (ID/GLP-1/18): sc-73508
- GLP-1 Antibody (ID/GLP-1/18) is a mouse monoclonal IgG1, cited in 3 publications, provided at 100 µg/ml
- raised against a synthetic peptide corresponding to amino acids 7-36 of GLP-1 of human origin
- recommended for detection of GLP-1 (7-36) amide and GLP-1 (1-30) amide of human origin by IF and IHC(P); non cross-reactive with GLP-2, GRPP, PYY, VIP, PHI, GIP, Glucagon, or Oxyntomodulin
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for GLP-1 Antibody (ID/GLP-1/18). This work is in progress.
GLP-1 Antibody (ID/GLP-1/18) is a mouse monoclonal IgG1 antibody that detects glucagon-like peptide-1 (GLP-1) in human samples through immunofluorescence (IF) and immunohistochemistry with paraffin-embedded sections (IHCP). GLP-1 plays a crucial role in glucose metabolism and appetite regulation, functioning as a key incretin hormone that enhances insulin secretion in response to meals while simultaneously inhibiting glucagon release, thereby lowering blood sugar levels. GLP-1 is primarily produced in the intestinal L-cells and is vital for maintaining glucose homeostasis, making GLP-1 an important target for diabetes research and therapeutic interventions. Additionally, GLP-1 is known to promote satiety and reduce food intake, which is significant for obesity management. The interaction of GLP-1 with GLP-1R initiates a cascade of intracellular signaling pathways that not only influence insulin secretion but also enhance beta-cell proliferation and survival, highlighting GLP-1′s potential in regenerative medicine. Anti-GLP-1 antibody (ID/GLP-1/18) is an essential tool for researchers investigating the physiological and pathological roles of GLP-1 in human health.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
GLP-1 Antibody (ID/GLP-1/18) | sc-73508 | 100 µg/ml | $322.00 |