FXR2 Antibody (55): sc-135912
- FXR2 Antibody (55) is a mouse monoclonal IgG2b provided at 50 µg/0.5 ml
- raised against amino acids 520-639 of FXR2 of human origin
- recommended for detection of FXR2 of mouse, rat and human origin by WB, IP and IF
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for FXR2 Antibody (55). This work is in progress.
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FXR2 Antibody (55) is a mouse monoclonal IgG2b antibody that detects FXR2 in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), and immunofluorescence (IF). FXR2 is a crucial RNA-binding protein that plays a significant role in mRNA metabolism regulation and is particularly important in fragile X syndrome, where FXR2 interacts with FMR1 protein and FXR1 to form heterodimers essential for proper neuronal function. FXR2 is primarily located in the cytoplasm, where FXR2 associates with polyribosomes, facilitating specific mRNA translation. This localization allows FXR2 to participate in local protein translation at synapses, which is critical for synaptic plasticity and cognitive function. Additionally, FXR2 contains two KH domains and an RGG box, which are characteristic features of RNA-binding proteins, enabling FXR2 to bind to RNA and influence RNA stability and translation. FXR2′s interaction with other fragile X syndrome-related proteins underscores FXR2′s importance in the molecular mechanisms underlying this condition, making anti-FXR2 antibody (55) an invaluable tool for researchers studying RNA-binding proteins and their roles in neurodevelopmental disorders.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
FXR2 Antibody (55) | sc-135912 | 50 µg/0.5 ml | $322.00 |