Date published: 2025-10-19

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Furaltadone (CAS 139-91-3)

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Alternate Names:
Furazolin; Nitrofurmethone; Altafur
Application:
Furaltadone is an antibacterial compound
CAS Number:
139-91-3
Molecular Weight:
324.29
Molecular Formula:
C13H16N4O6
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Furaltadone, a nitrofuran derivative, has been extensively studied in scientific research for its antimicrobial properties and mechanisms of action. Research indicates that Furaltadone exerts its antibacterial effects primarily by interfering with microbial DNA replication and protein synthesis. Specifically, it acts as a prodrug that undergoes metabolic activation within bacterial cells, forming reactive intermediates that target essential enzymes involved in DNA synthesis, such as DNA gyrase and topoisomerase II. This disruption of DNA replication leads to DNA damage and ultimately bacterial cell death. Additionally, Furaltadone has been investigated for its potential as a growth promoter in animal husbandry, particularly in poultry farming. Studies have explored its efficacy in preventing and treating bacterial infections in livestock, contributing to improved animal health and productivity. Furthermore, Furaltadone′s broad-spectrum antimicrobial activity has been leveraged in environmental research for water treatment applications, where it helps control microbial contamination and prevent the spread of waterborne diseases. Ongoing research continues to unravel the precise molecular mechanisms of Furaltadone′s antimicrobial action and explore its diverse applications in agriculture, animal husbandry, and environmental science.


Furaltadone (CAS 139-91-3) References

  1. Furaltadone. A critical evaluation of clinical and laboratory studies.  |  McCabe, WR., et al. 1960. N Engl J Med. 263: 927-34. PMID: 13773736
  2. Furaltadone (Valsyn Gel) Dans Le Traitement des Mammites Bovines.  |  Filion, R. and Phaneuf, JB. 1962. Can Vet J. 3: 340-2. PMID: 17421543
  3. Furaltadone suppresses IgE-mediated allergic response through the inhibition of Lyn/Syk pathway in mast cells.  |  Nam, ST., et al. 2018. Eur J Pharmacol. 828: 119-125. PMID: 29588153
  4. Investigation of electrocatalytic and photocatalytic ability of Cu/Ni/TiO2/MWCNTs Nanocomposites for detection and degradation of antibiotic drug Furaltadone.  |  Vasu, D., et al. 2022. Sci Rep. 12: 886. PMID: 35042930
  5. One-step synthesis of blue emission copper nanoclusters for the detection of furaltadone and temperature.  |  Cai, ZF., et al. 2022. Spectrochim Acta A Mol Biomol Spectrosc. 279: 121408. PMID: 35617839
  6. UV/solar photo-degradation of furaltadone in homogeneous and heterogeneous phases: Intensification with persulfate.  |  Durán, A., et al. 2022. J Environ Manage. 319: 115712. PMID: 35849926
  7. Hierarchical 3D Snowflake-like Iron Diselenide: A Robust Electrocatalyst for Furaltadone Detection.  |  Sakthi Priya, T., et al. 2023. Inorg Chem. 62: 1437-1446. PMID: 36652943
  8. Blue-emitting tryptophan-protected gold nanoclusters acted as a sensitive nanosensor for fluorescence sensing and visual imaging detection of furaltadone.  |  Cai, Z., et al. 2024. Spectrochim Acta A Mol Biomol Spectrosc. 308: 123748. PMID: 38091651
  9. Aqueous fate of furaltadone: Kinetics, high-resolution mass spectrometry - based elucidation and toxicity assessment of photoproducts.  |  Efthymiou, C., et al. 2024. Sci Total Environ. 919: 170848. PMID: 38340835
  10. Biotransformation of furaltadone by pig hepatocytes and Salmonella typhimurium TA 100 bacteria, and the formation of protein-bound metabolites.  |  Hoogenboom, LA., et al. 1994. Xenobiotica. 24: 713-27. PMID: 7839695

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Furaltadone, 25 g

sc-215062
25 g
$52.00