Date published: 2025-10-19

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Formic acid solution (CAS 64-18-6)

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Application:
Formic acid solution is 1.0 M in H2O, a volatile pH modifier in HPLC and CE; also a preservative and antibacterial agent
CAS Number:
64-18-6
Molecular Weight:
46.03
Molecular Formula:
CH2O2
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Formic acid solution, a colorless liquid with a pungent odor, is a versatile chemical compound with diverse industrial, agricultural, and research applications. Also known as methanoic acid, it is composed of a single carbon atom bonded to two oxygen atoms (HCOOH) and is the simplest carboxylic acid. Formic acid solution finds applications as a preservative, disinfectant, and pH adjuster in various processes. It is used in the production of leather, textiles, and rubber, where it serves as a tanning agent, pH regulator, and coagulant. Additionally, formic acid solution is employed as a descaling agent in the cleaning of industrial equipment and as a chemical intermediate in the synthesis of pharmaceuticals, pesticides, and dyes. In research, formic acid solution is a valuable reagent in various scientific disciplines. In chemistry, it is used as a reducing agent, catalyst, and solvent for organic synthesis reactions. In biochemistry, formic acid solution is employed in protein extraction and digestion protocols, particularly in mass spectrometry-based proteomics workflows. Additionally, it finds applications in analytical chemistry, where it is used as a mobile phase additive in high-performance liquid chromatography (HPLC) and gas chromatography (GC) analyses. The properties of formic acid solution make it a versatile and indispensable reagent in numerous industrial and scientific applications. Ongoing research focuses on optimizing its production methods, exploring new applications, and understanding its environmental and health impacts.


Formic acid solution (CAS 64-18-6) References

  1. The role of formic acid in solution stability and crystallization of silk protein polymer.  |  Um, IC., et al. 2003. Int J Biol Macromol. 33: 203-13. PMID: 14607365
  2. RNA preservation in decalcified cochlear samples.  |  Waissbluth, S., et al. 2013. Otol Neurotol. 34: 331-7. PMID: 23250382
  3. Preparation and characterization of gelatin nanofibers containing silver nanoparticles.  |  Jeong, L. and Park, WH. 2014. Int J Mol Sci. 15: 6857-79. PMID: 24758929
  4. Hydrogen production from formic acid solution by modified TiO2 and titanate nanotubes in a two-step system under visible light irradiation.  |  Yeh, HM., et al. 2014. Water Sci Technol. 69: 1676-81. PMID: 24759528
  5. Facile fabrication of robust silk nanofibril films via direct dissolution of silk in CaCl2-formic acid solution.  |  Zhang, F., et al. 2015. ACS Appl Mater Interfaces. 7: 3352-61. PMID: 25603225
  6. Effects of solvent on the solution properties, structural characteristics and properties of silk sericin.  |  Jo, YN. and Um, IC. 2015. Int J Biol Macromol. 78: 287-95. PMID: 25869308
  7. Boosting CdS Photocatalytic Activity for Hydrogen Evolution in Formic Acid Solution by P Doping and MoS2 Photodeposition.  |  Liu, J., et al. 2022. Nanomaterials (Basel). 12: PMID: 35159906
  8. Formylation: an undesirable modification on glycopeptides and glycans during storage in formic acid solution.  |  Zhi, Y., et al. 2022. Anal Bioanal Chem. 414: 3311-3317. PMID: 35229171
  9. Establishment to measure oxycodone in plasma with liquid chromatography-tandem mass spectrometry.  |  Ito, S., et al. 2022. Neuropsychopharmacol Rep. 42: 299-305. PMID: 35689429
  10. Highly Efficient Fractionation of Cornstalk into Noncondensed Lignin, Xylose, and Cellulose in Formic Acid.  |  Xie, X., et al. 2022. J Agric Food Chem. 70: 15430-15438. PMID: 36458728

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Formic acid solution, 100 ml

sc-294988
100 ml
$254.00