Date published: 2025-12-4

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Fmoc-Val-OH (CAS 68858-20-8)

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Alternate Names:
Fmoc-L-valine
Application:
Fmoc-Val-OH is an Fmoc protected valine derivative
CAS Number:
68858-20-8
Molecular Weight:
339.39
Molecular Formula:
C20H21NO4
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Fmoc-Val-OH is a chemical compound that functions as a protecting group in peptide synthesis. It is used to block the reactive functional groups of amino acids, allowing for selective reactions to occur at specific sites within the peptide chain. This compound attaches to the amino group of the valine residue, preventing unwanted side reactions during the peptide assembly process. By serving as a protective shield, Fmoc-Val-OH enables precise control over the sequence and structure of the synthesized peptide. Its mode of action involves forming stable covalent bonds with the amino acid, effectively masking its reactivity until the deprotection step. This allows for the stepwise elongation of the peptide chain, ensuring the desired sequence is achieved without interference from other reactive groups.


Fmoc-Val-OH (CAS 68858-20-8) References

  1. New 4-Aminoproline-Based Small Molecule Cyclopeptidomimetics as Potential Modulators of α4β1 Integrin.  |  Sartori, A., et al. 2021. Molecules. 26: PMID: 34641610
  2. Engineering Enzyme-Cleavable Oligonucleotides by Automated Solid-Phase Incorporation of Cathepsin B Sensitive Dipeptide Linkers.  |  Jin, C., et al. 2022. Angew Chem Int Ed Engl. 61: e202114016. PMID: 34953094
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  7. Dipropylamine for 9-Fluorenylmethyloxycarbonyl (Fmoc) Deprotection with Reduced Aspartimide Formation in Solid-Phase Peptide Synthesis.  |  Personne, H., et al. 2023. ACS Omega. 8: 5050-5056. PMID: 36777595
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Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Fmoc-Val-OH, 50 g

sc-235209
50 g
$102.00