Date published: 2026-4-25

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Fmoc-D-aspartic acid (CAS 136083-57-3)

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Alternate Names:
Fmoc-D-Asp-OH
CAS Number:
136083-57-3
Molecular Weight:
355.35
Molecular Formula:
C19H17NO6
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Fmoc-D-aspartic acid is an amino acid derivative that has held a pivotal role in synthetic peptide chemistry since the early 2000s. Derived from the naturally occurring amino acid D-Aspartic Acid, this compound provides a safeguarded version of its source. Demonstrating impressive versatility, Fmoc-D-aspartic acid has found its utility across a spectrum of laboratory experiments and scientific inquiries. The versatility of Fmoc-D-aspartic acid manifests in a diverse array of scientific research domains. Within peptide synthesis, it serves as a fundamental building block for the construction of peptides and proteins. In parallel, its role extends to nucleic acid synthesis, contributing as a foundational component for the assembly of DNA and RNA structures. Beyond this, Fmoc-D-aspartic acid extends its influence to drug design, where it stands as a prototypical compound. Additionally, it finds application within enzyme-catalyzed reactions, proficiently acting as an inhibitor of enzymes and assorted proteins. The modus operandi of Fmoc-D-aspartic acid varies with its application. In the realm of peptide synthesis, its function is pivotal as it contributes to the creation of peptides and proteins. As part of nucleic acid synthesis, it shoulders the responsibility of shaping the framework of DNA and RNA molecules. When harnessed in the realm of drug design, it serves as a representative template, guiding the conception of innovative therapeutic agents. Notably, in the realm of enzyme-catalyzed reactions, it undertakes the role of an effective inhibitor, perturbing the function of enzymes and other proteins to elicit specific responses.


Fmoc-D-aspartic acid (CAS 136083-57-3) References

  1. [Peptide fragment 66-77 of monocyte chemoattractant protein 1 and its retro-enantio analogue inhibits the migration of cells in vitro and in vivo].  |  Sidorova, MV., et al. 2006. Bioorg Khim. 32: 161-8. PMID: 16637287
  2. Chiral capillary electrophoresis with UV-excited fluorescence detection for the enantioselective analysis of 9-fluorenylmethoxycarbonyl-derivatized amino acids.  |  Prior, A., et al. 2018. Anal Bioanal Chem. 410: 4979-4990. PMID: 29808298
  3. Development of a new class of PSMA radioligands comprising ibuprofen as an albumin-binding entity.  |  Deberle, LM., et al. 2020. Theranostics. 10: 1678-1693. PMID: 32042329
  4. Novel Cyclic Lipopeptides Fusaricidin Analogs for Treating Wound Infections.  |  Gil, J., et al. 2021. Front Microbiol. 12: 708904. PMID: 34367114

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Fmoc-D-aspartic acid, 1 g

sc-285708
1 g
$28.00

Fmoc-D-aspartic acid, 5 g

sc-285708A
5 g
$92.00