Molecular structure of Fluphenazine Hydrochloride, CAS Number: 146-56-5
Fluphenazine Hydrochloride (CAS 146-56-5)
Alternate Names:
Fluphenazine Hydrochloride is also known as SQ 4,918.
Application:
Fluphenazine Hydrochloride is a dopamine D1 and D2 receptor antagonist that can bind to histamine H1
CAS Number:
146-56-5
Purity:
≥97%
Molecular Weight:
510.44
Molecular Formula:
C22H26F3N3OS•2HCl
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
Fluphenazine is a chemical compound that functions as a dopamine antagonist in experimental applications. It exerts its mode of action by blocking dopamine receptors in the brain, targeting the D2 subtype. This interaction inhibits the transmission of dopamine signals, leading to altered neurotransmission within the central nervous system. By modulating dopamine activity, fluphenazine can impact various physiological processes in experimental models. Its mechanism of action involves binding to dopamine receptors and interfering with the normal signaling pathways, ultimately influencing neuronal activity and neurotransmitter release. Fluphenazine′s functional role lies in its ability to manipulate dopamine neurotransmission.
Fluphenazine Hydrochloride (CAS 146-56-5) References
- Spectrofluorometric determination of olanzapine and fluphenazine hydrochloride in pharmaceutical preparations and human plasma using eosin: application to stability studies. | Belal, F., et al. 2008. J AOAC Int. 91: 1309-17. PMID: 19202791
- Second-derivative synchronous fluorescence spectroscopy for the simultaneous determination of fluphenazine hydrochloride and nortriptyline hydrochloride in pharmaceutical preparations. | Walash, MI., et al. 2009. J Fluoresc. 19: 891-904. PMID: 19418209
- Simultaneous chemiluminescence determination of promazine and fluphenazine using support vector regression. | Ensafi, AA., et al. 2009. Talanta. 79: 534-8. PMID: 19559917
- Forced Degradation Behaviour of Fluphenazine Hydrochloride by LC and Characterization of its Oxidative Degradation Product by LC-MS/MS. | Thummar, KN., et al. 2015. Sci Pharm. 83: 297-309. PMID: 26839816
- Simultaneous determination of nortriptyline hydrochloride and fluphenazine hydrochloride in microgram quantities from low dosage forms by liquid chromatography-UV detection. | Ashour, S. and Kattan, N. 2012. J Pharm Anal. 2: 437-442. PMID: 29403779
- Experience with fluphenazine hydrochloride injection. | Zabow, T. 1985. S Afr Med J. 67: 118. PMID: 3969594
- Priapism resulting from fluphenazine hydrochloride treatment reversed by diphenhydramine. | Fishbain, DA. 1985. Ann Emerg Med. 14: 600-2. PMID: 3994089
- Fluphenazine hydrochloride and enanthate in the management of chronic psychosis. | Polvan, N. 1970. Dis Nerv Syst. 31: Suppl:48-9. PMID: 5476359
- Fluphenazine hydrochloride in small doses. | Bucci, L. 1968. Psychosomatics. 9: 344-5. PMID: 5725618
- Effects of fluphenazine hydrochloride on the bone-marrow cells of Swiss mice. | Rao, KP. and Rao, MS. 1981. Mutat Res. 89: 237-40. PMID: 7266572
- Fluphenazine decanoate and tardive dyskinesia: a possible association. | Csernansky, JG., et al. 1981. Am J Psychiatry. 138: 1362-5. PMID: 7294195
- Plasma fluphenazine levels measured by high-performance liquid chromatography in patients treated with depot injections. | Jouen, F., et al. 1993. Arzneimittelforschung. 43: 509-11. PMID: 8328993
- Severe rhinorrhea and respiratory distress in a neonate exposed to fluphenazine hydrochloride prenatally. | Nath, SP., et al. 1996. Ann Pharmacother. 30: 35-7. PMID: 8773163
Inhibitor of:
D1DR, D2DR, D5DR, and Histamine H1 Receptor.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Fluphenazine Hydrochloride, 1 g | sc-205700 | 1 g | $209.00 | |||
Fluphenazine Hydrochloride, 5 g | sc-205700A | 5 g | $463.00 | |||
Fluphenazine Hydrochloride, 50 g | sc-205700B | 50 g | $1046.00 | |||
Fluphenazine Hydrochloride, 100 g | sc-205700C | 100 g | $1569.00 |