Flubendazole CAS: 31430-15-6
MF: C16H12FN3O3
MW: 313.28
An insectocidal agent.

Flubendazole (CAS 31430-15-6)

Flubendazole | CAS 31430-15-6 is rated 5.0 out of 5 by 1.
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Alternate Names: Flumoxanal; Methyl [5-(4-fluorobenzoyl)-1H-benzimidazol-2-yl]carbamate
Application: Flubendazole is an insectocidal agent
CAS Number: 31430-15-6
Purity: ≥98%
Molecular Weight: 313.28
Molecular Formula: C16H12FN3O3
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data (including water content).

Flubendazole is a potent broad spectrum anthelmintic.


References

William S, Guirguis F, Nessim NG. Arzneimittelforschung. 53:532-7 (2003).

Appearance :
Crystalline
Physical State :
Solid
Solubility :
Soluble in water (<1 mg/ml at 25° C), DMSO (1 mg/ml at 25° C), ethanol (<1 mg/ml at 25° C), and hot acetic acid.
Storage :
Store at 4° C
Melting Point :
260° C (lit.)
Boiling Point :
520.47° C (Predicted)
Density :
~1.4 g/cm3 (Predicted)
Refractive Index :
n20D 1.69 (Predicted)
IC50 :
Anthelmintic agent for MDAY-D2 cells: IC50 = 3 nM; HIV-1(RF): IC50 = 85.3 nM (CEM); Inhibitors of 5'UTR Stem-Loop Driven Prion Protein mRNA Translation: EC5050 = 225 nM (H4 neuroglioblastoma cells); Inhibitors of Luciferase Translation or Activity: EC5050 = 323 nM (H4 neuroglioblastoma cells)
pK Values :
pKa: 10.66 (Predicted), pKb: 4.45 (Predicted)
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
WGK Germany :
2
RTECS :
DD6497500
PubChem CID :
35802
Merck Index :
14: 4118
MDL Number :
MFCD00871999
EC Number :
250-624-4
SMILES :
COC(=O)Nc1[nH]c2ccc(cc2n1)C(=O)c1ccc(F)cc1

Download SDS (MSDS)

Certificate of Analysis

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Flubendazole (CAS 31430-15-6)  Product Citations

See how others have used Flubendazole (CAS 31430-15-6). Click on the entry to view the PubMed entry .

Citations 1 to 3 of 3 total

PMID: # 30664786  Liu, PH.|Shah, RB.|Li, Y.|Arora, A.|Ung, PM.|Raman, R.|Gorbatenko, A.|Kozono, S.|Zhou, XZ.|Brechin, V.|Barbaro, JM.|Thompson, R.|White, RM.|Aguirre-Ghiso, JA.|Heymach, JV.|Lu, KP.|Silva, JM.|Panageas, KS.|Schlessinger, A.|Maki, RG.|Skinner, HD.|de Stanchina, E.|Sidi, S.| et al. 2019. Nat. Cell Biol.

PMID: # 24890838  Wagil, M. et al. 2015. Chemosphere. 119 Suppl: S35-41.

PMID: # 25189803  Wagil, M. et al. 2015. Environ Sci Pollut Res Int. 22: 2566-73.

Citations 1 to 3 of 3 total

Can i, before I place an order, see of the reference standard has a accreditation NEN17025?

Asked by: Maarten
Thank you for your question. Please contact technical service so we can send you a certificate of analysis of the most recent lot of this product.
Answered by: SCBT Heidelberg Support
Date published: 2019-01-06

What is the appearance of the chemical?

Asked by: two2igm05
Thank you for your question. The compound, sc-204754, is provided as a white to off-white powder. If you have any further questions or concerns, please feel free to contact our Technical Service department by calling 800-457-3801 option 2, emailing [email protected] or using the Live Chat function on our website.
Answered by: Tech Service 8
Date published: 2017-01-19
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Rated 5 out of 5 by from Spagnuolo Spagnuolo, PA. et al. (PubMed 20348394) reported that the antihelmintic Flubendazole inhibits microtubule function through a mechanism distinct from Vinca alkaloids and displays preclinical activity in leukemia and myeloma. -SCBT Publication Review
Date published: 2015-02-16
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