Fibrinogen Antibody (40F11): sc-51895
- Fibrinogen Antibody (40F11) is a mouse monoclonal IgG1 provided at 100 µg/ml
- raised against fibrin degradation products of human origin
- recommended for detection of whole Fibrinogen, consisting of a dimer of three pairs of non-identical chains, α, β and γ, and Fibrin degradation products of human origin by WB and IP
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for Fibrinogen Antibody (40F11). This work is in progress.
QUICK LINKS
Fibrinogen Antibody (40F11) is a mouse monoclonal IgG1 antibody that detects Fibrinogen in human samples through western blotting (WB) and immunoprecipitation (IP) applications. Fibrinogen is a crucial plasma glycoprotein synthesized in the liver, consisting of three distinct subunits: α, β, and γ. Fibrinogen plays a vital role in the coagulation cascade, particularly in platelet aggregation and the formation of Fibrin, which is essential for blood clotting and maintaining hemostasis following tissue injury. The structure of Fibrinogen is significant because its unique arrangement allows for effective interaction with various procoagulants, such as Prothrombin and Factors X, IX, V, and VIII, facilitating the conversion of Fibrinogen into Fibrin by Thrombin. This conversion is not only critical for forming stable blood clots but also for regulating cell adhesion and spreading, as well as exhibiting vasoconstrictor and chemotactic properties. The cleavage products of Fibrinogen further enhance its importance by acting as mitogens for several cell types, thereby influencing wound healing and tissue repair processes. Anti-Fibrinogen antibody (40F11) is an invaluable tool for researchers studying coagulation mechanisms and related pathologies, providing insights into the complex interplay of proteins involved in hemostasis.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Fibrinogen Antibody (40F11) | sc-51895 | 100 µg/ml | $322.00 |