FAM90A Antibody (A-8): sc-393598
- FAM90A Antibody (A-8) is a mouse monoclonal IgG1 κ FAM90A antibody provided at 200 µg/ml
- specific for an epitope mapping between amino acids 372-399 within an internal region of FAM90A8 of human origin
- FAM90A Antibody (A-8) is recommended for detection of a broad range of FAM90A family members of human origin by WB, IP, IF and ELISA
- Anti-FAM90A Antibody (A-8) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- m-IgG1 BP-HRP is the preferred secondary detection reagent for FAM90A Antibody (A-8) for WB applications. This reagent is now offered in a bundle with FAM90A Antibody (A-8) (see ordering information below).
QUICK LINKS
FAM90A Antibody (A-8) is a mouse monoclonal IgG1 kappa light chain antibody that detects FAM90A protein of human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). FAM90A Antibody (A-8) is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. FAM90A protein is located in the nucleus and plays a crucial role in regulating gene expression and cellular responses to stress, which is vital for maintaining cellular homeostasis and preventing diseases such as cancer. Dysregulation of FAM90A has been implicated in various malignancies, highlighting FAM90A′s potential as a biomarker for cancer diagnosis and prognosis. Additionally, chromosome 8, which encodes FAM90A gene, is associated with several genetic disorders and conditions, including certain leukemias and lymphomas, as well as neurodevelopmental disorders like schizophrenia and bipolar disorder. FAM90A gene product has been provisionally designated FAM90A pending further characterization, and ongoing research continues to explore FAM90A′s functional significance and potential therapeutic applications.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
FAM90A Antibody (A-8) References:
- Chromosomes 8 and 10 workshop. | Wildenauer, DB. and Schwab, SG. 1999. Am J Med Genet. 88: 239-43. PMID: 10374738
- Preferential expression of an intact WRN gene in Werner syndrome cell lines in which a normal chromosome 8 has been introduced. | Kashino, G., et al. 2001. Biochem Biophys Res Commun. 289: 111-5. PMID: 11708785
- Cytogenetic mapping of a novel locus for type II Waardenburg syndrome. | Selicorni, A., et al. 2002. Hum Genet. 110: 64-7. PMID: 11810298
- Combined analysis from eleven linkage studies of bipolar disorder provides strong evidence of susceptibility loci on chromosomes 6q and 8q. | McQueen, MB., et al. 2005. Am J Hum Genet. 77: 582-95. PMID: 16175504
- DNA sequence and analysis of human chromosome 8. | Nusbaum, C., et al. 2006. Nature. 439: 331-5. PMID: 16421571
- Epigenetic inactivation of the premature aging Werner syndrome gene in human cancer. | Agrelo, R., et al. 2006. Proc Natl Acad Sci U S A. 103: 8822-7. PMID: 16723399
- Non-Hodgkin's lymphomas with Burkitt-like cells are associated with c-Myc amplification and poor prognosis. | Mossafa, H., et al. 2006. Leuk Lymphoma. 47: 1885-93. PMID: 17065002
- Characterization and evolution of the novel gene family FAM90A in primates originated by multiple duplication and rearrangement events. | Bosch, N., et al. 2007. Hum Mol Genet. 16: 2572-82. PMID: 17684299
- Postnatal development- and age-related changes in DNA-methylation patterns in the human genome. | Salpea, P., et al. 2012. Nucleic Acids Res. 40: 6477-94. PMID: 22495928
- The effect of host genetics on the gut microbiome. | Bonder, MJ., et al. 2016. Nat Genet. 48: 1407-1412. PMID: 27694959
- Integrated analysis of DNA methylation and mRNA expression profiles to identify key genes involved in the regrowth of clinically non-functioning pituitary adenoma. | Cheng, S., et al. 2020. Aging (Albany NY). 12: 2408-2427. PMID: 32015217
- Alterations in phospholipid-dependent (Na+ +K+)-ATPase activity due to lipid fluidity. Effects of cholesterol and Mg2+. | Kimelberg, HK. 1975. Biochim Biophys Acta. 413: 143-56. PMID: 90
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
FAM90A Antibody (A-8) | sc-393598 | 200 µg/ml | $316.00 | |||
FAM90A Antibody (A-8): m-IgG1 BP-HRP Bundle | sc-531762 | 200 µg Ab; 20 µg BP | $354.00 | |||
FAM90A Antibody (A-8) AC | sc-393598 AC | 500 µg/ml, 25% agarose | $416.00 | |||
FAM90A Antibody (A-8) HRP | sc-393598 HRP | 200 µg/ml | $316.00 | |||
FAM90A Antibody (A-8) FITC | sc-393598 FITC | 200 µg/ml | $330.00 | |||
FAM90A Antibody (A-8) PE | sc-393598 PE | 200 µg/ml | $343.00 | |||
FAM90A Antibody (A-8) Alexa Fluor® 488 | sc-393598 AF488 | 200 µg/ml | $357.00 | |||
FAM90A Antibody (A-8) Alexa Fluor® 546 | sc-393598 AF546 | 200 µg/ml | $357.00 | |||
FAM90A Antibody (A-8) Alexa Fluor® 594 | sc-393598 AF594 | 200 µg/ml | $357.00 | |||
FAM90A Antibody (A-8) Alexa Fluor® 647 | sc-393598 AF647 | 200 µg/ml | $357.00 | |||
FAM90A Antibody (A-8) Alexa Fluor® 680 | sc-393598 AF680 | 200 µg/ml | $357.00 | |||
FAM90A Antibody (A-8) Alexa Fluor® 790 | sc-393598 AF790 | 200 µg/ml | $357.00 | |||
FAM90A (A-8) Neutralizing Peptide | sc-393598 P | 100 µg/0.5 ml | $68.00 |