Date published: 2025-12-14

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Ethyl β-D-Glucuronide (CAS 17685-04-0)

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Alternate Names:
6-Ethoxy-3,4,5-trihydroxy-tetrahydropyran-2-carboxylic acid
Application:
Ethyl β-D-Glucuronide is a useful marker of alcohol consumption
CAS Number:
17685-04-0
Purity:
≥90%
Molecular Weight:
222.19
Molecular Formula:
C8H14O7
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Ethyl β-D-glucuronide is a reference standard for the detection of alcohol metabolites in blood or urine. The compound is intended for the calibration and quantification of glucuronide metabolites of alcohol when using GC-MS, LC-MS or HPLC methodology. Ethyl β-D-Glucuronide has a wide range of potential applications including law enforcement, forensics, employment screening and testing of racehorses.


Ethyl β-D-Glucuronide (CAS 17685-04-0) References

  1. Can ethyl glucuronide be determined in post-mortem body fluids and tissues?  |  Wurst, FM., et al. 1999. Alcohol Alcohol. 34: 262-3. PMID: 10344787
  2. Excretion profiles of ethyl glucuronide in human urine after internal dilution.  |  Goll, M., et al. 2002. J Anal Toxicol. 26: 262-6. PMID: 12166812
  3. Ethyl glucuronide--the direct ethanol metabolite on the threshold from science to routine use.  |  Wurst, FM., et al. 2003. Addiction. 98 Suppl 2: 51-61. PMID: 14984242
  4. Analysis of ethyl glucuronide in human serum by capillary electrophoresis with sample self-stacking and indirect detection.  |  Krivánková, L., et al. 2005. J Chromatogr A. 1081: 2-8. PMID: 16013590
  5. Identification of noninvasive biomarkers for alcohol-induced liver disease using urinary metabolomics and the Ppara-null mouse.  |  Manna, SK., et al. 2010. J Proteome Res. 9: 4176-88. PMID: 20540569
  6. UPLC-MS-based urine metabolomics reveals indole-3-lactic acid and phenyllactic acid as conserved biomarkers for alcohol-induced liver disease in the Ppara-null mouse model.  |  Manna, SK., et al. 2011. J Proteome Res. 10: 4120-33. PMID: 21749142
  7. Glucuronic acid and the ethanol metabolite ethyl-glucuronide cause toll-like receptor 4 activation and enhanced pain.  |  Lewis, SS., et al. 2013. Brain Behav Immun. 30: 24-32. PMID: 23348028
  8. Cross-reaction of propyl and butyl alcohol glucuronides with an ethyl glucuronide enzyme immunoassay.  |  Arndt, T., et al. 2014. Forensic Sci Int. 241: 84-6. PMID: 24887323
  9. Select steroid hormone glucuronide metabolites can cause toll-like receptor 4 activation and enhanced pain.  |  Lewis, SS., et al. 2015. Brain Behav Immun. 44: 128-36. PMID: 25218902
  10. Application of mass spectrometry-based metabolomics in identification of early noninvasive biomarkers of alcohol-induced liver disease using mouse model.  |  Manna, SK., et al. 2015. Adv Exp Med Biol. 815: 217-38. PMID: 25427910
  11. Decoy peptide targeted to Toll-IL-1R domain inhibits LPS and TLR4-active metabolite morphine-3 glucuronide sensitization of sensory neurons.  |  Allette, YM., et al. 2017. Sci Rep. 7: 3741. PMID: 28623271
  12. Decrease of ethyl glucuronide concentrations in hair after exposure to chlorinated swimming pool water.  |  Luginbühl, M., et al. 2018. Drug Test Anal. 10: 689-693. PMID: 28856820
  13. Monitoring of direct alcohol markers in alcohol use disorder patients during withdrawal treatment and successive rehabilitation.  |  Luginbühl, M., et al. 2019. Drug Test Anal. 11: 859-869. PMID: 30618164

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Ethyl β-D-Glucuronide, 10 mg

sc-221597
10 mg
$388.00

Ethyl β-D-Glucuronide, 50 mg

sc-221597A
50 mg
$918.00

Ethyl β-D-Glucuronide, 100 mg

sc-221597B
100 mg
$1428.00

Ethyl β-D-Glucuronide, 500 mg

sc-221597C
500 mg
$6125.00