Date published: 2025-9-30

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Ethyl 2-amino-benzothiazole-6-carboxylate (CAS 50850-93-6)

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Alternate Names:
2-Aminobenzothiazole-6-carboxylic acid ethyl ester
CAS Number:
50850-93-6
Molecular Weight:
222.26
Molecular Formula:
C10H10N2O2S
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Ethyl 2-amino-benzothiazole-6-carboxylate is a heterocyclic compound known for its potential as a versatile intermediate in organic synthesis. Its mechanism of action primarily involves the formation of stable conjugates through its amino and carboxylate functional groups, enabling it to participate in various chemical reactions. This compound is particularly valuable in the synthesis of biologically active molecules, including pharmaceuticals and agrochemicals. In research, ethyl 2-amino-benzothiazole-6-carboxylate is used to explore the development of new materials and chemical entities. It serves as a building block in the synthesis of benzothiazole derivatives, which are studied for their electronic, photophysical, and catalytic properties. Researchers employ this compound to investigate the structure-activity relationships (SAR) of benzothiazole derivatives, aiming to enhance their functional properties for specific applications. Additionally, ethyl 2-amino-benzothiazole-6-carboxylate is utilized in the study of coordination chemistry, where it acts as a ligand to form metal complexes. These complexes are analyzed for their potential applications in catalysis, sensing, and material science. The compound′s role in facilitating the synthesis of diverse chemical structures makes it a valuable tool in advancing the fields of organic and inorganic chemistry, contributing to the discovery and development of new chemical entities.


Ethyl 2-amino-benzothiazole-6-carboxylate (CAS 50850-93-6) References

  1. Synthesis of potent and selective inhibitors of Candida albicans N-myristoyltransferase based on the benzothiazole structure.  |  Yamazaki, K., et al. 2005. Bioorg Med Chem. 13: 2509-22. PMID: 15755653
  2. Identification of benzothiazoles as novel PCSK9 inhibitors.  |  Ma, Z., et al. 2024. Bioorg Med Chem Lett. 97: 129542. PMID: 37939861
  3. Transmission of substituent effects in heterocyclic systems by carbon-13 nuclear magnetic resonance. Benzothiazoles  |  Sawhney, S. N., & Boykin, D. W. 1979. The Journal of Organic Chemistry. 44(7): 1136-1142.

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Ethyl 2-amino-benzothiazole-6-carboxylate, 1 g

sc-396404
1 g
$60.00