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Erythromycin A N-oxide, bearing the CAS number 992-65-4, represents a chemically modified form of the well-known compound erythromycin A, distinguished by the addition of an N-oxide group. This modification profoundly impacts the molecule′s chemical properties and its interaction with biological systems. Specifically, the introduction of the N-oxide group alters the electron distribution within the molecule, which can affect its binding affinity and mechanism of action relative to its unmodified counterpart. In biochemical research, Erythromycin A N-oxide has been used predominantly to investigate the role of oxidative modifications in the activity and stability of macrolide antibiotics. This compound serves as a crucial tool in studies focusing on the metabolic pathways involving erythromycin and similar substances, particularly how these pathways can be influenced by enzymatic activities that introduce oxygen-containing groups into the molecular structure. Researchers utilize Erythromycin A N-oxide to explore how such modifications can affect the interaction of macrolides with bacterial ribosomes—the primary site of action for this class of molecules. Understanding these interactions provides valuable insights into the molecular dynamics of ribosome function and the potential mechanisms by which bacteria may develop resistance to certain types of antibiotics. This research is essential for advancing fundamental knowledge in microbiology and enzymology, shedding light on the subtle nuances of antibiotic action and resistance.
Ordering Information
Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Erythromycin A N-oxide, 5 mg | sc-391531 | 5 mg | $71.00 | |||
Erythromycin A N-oxide, 25 mg | sc-391531A | 25 mg | $288.00 |