EphA7 (h2): 293T Lysate: sc-158479

The EphA7 (h2): 293T Lysate is derived from the HEK293T cell line, a human embryonic kidney cell line renowned for its high transfection efficiency and utility in various research applications. This lysate contains Ephrin type-A receptor 7 (EphA7), a member of the Eph receptor tyrosine kinase family, which plays a crucial role in cell signaling related to development, especially in the nervous system. EphA7 interacts with ephrin-A ligands on adjacent cells, leading to bidirectional signaling that influences cell adhesion, shape, and mobility. This receptor-ligand interaction is pivotal in axon guidance, boundary formation, and cell sorting during embryonic development. In research, the EphA7 (h2): 293T Lysate is used to study the molecular mechanisms of Eph/ephrin signaling. Researchers utilize this lysate to investigate the protein-protein interactions, phosphorylation events, and downstream signaling pathways activated by EphA7 engagement. It is particularly valuable in in vitro assays to examine the role of EphA7 in neural development and cell migration, as well as its influence on synaptic plasticity and network formation. Additionally, the lysate aids in screening for potential modulators of EphA7 activity, providing insights into how this receptor regulates cellular processes. By leveraging this lysate, scientists can deepen their understanding of the complexities of EphA7 signaling and its broader implications in developmental biology and cell communication.