ent-Abacavir (CAS 136470-79-6)
Alternate Names:
(1R,4S)-4-[2-Amino-6-(cyclopropylamino)-9H-purin-9-yl]-2-cyclopentene-1-methano
Application:
ent-Abacavir is an enatiomer of the nucleoside reverse transcriptase inhibitor (NRTI) Abacavir
CAS Number:
136470-79-6
Molecular Weight:
286.33
Molecular Formula:
C14H18N6O
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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Description
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SDS & Certificate of Analysis
ent-Abacavir is the enatiomer of the nucleoside reverse transcriptase inhibitor (NRTI) Abacavir [also called Ziagen (sc-338739)] with similar antiviral properties. NRTIs work by blocking HIV reverse transcriptase (HIV-1 RT), an HIV enzyme.
ent-Abacavir (CAS 136470-79-6) References
- Interaction of guanine phosphonomethoxyalkyl derivatives with GMP kinase isoenzymes. | Krejcová, R., et al. 2000. Biochem Pharmacol. 60: 1907-13. PMID: 11108807
- Phosphonomethoxyalkyl analogs of nucleotides. | Holy, A. 2003. Curr Pharm Des. 9: 2567-92. PMID: 14529543
- Antiviral drugs in wastewater and surface waters: a new pharmaceutical class of environmental relevance? | Prasse, C., et al. 2010. Environ Sci Technol. 44: 1728-35. PMID: 20108960
- Phospholipidosis as a function of basicity, lipophilicity, and volume of distribution of compounds. | Hanumegowda, UM., et al. 2010. Chem Res Toxicol. 23: 749-55. PMID: 20356072
Inhibitor of:
HIV-1 RT.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
ent-Abacavir, 5 mg | sc-479383 | 5 mg | $430.00 |