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DL-Citrulline (CAS 627-77-0)

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Alternate Names:
DL-2-Amino-5-ureidovaleric acid
Application:
DL-Citrulline is DL-Citrulline is an α amino acid. Citrulline can be converted to arginine, which is a precursor for nitric oxide. Several proteins contain citrulline as a result of a posttranslational modification.
CAS Number:
627-77-0
Purity:
≥96%
Molecular Weight:
175.19
Molecular Formula:
C6H13N3O3
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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DL-Citrulline is an alpha amino acid. Citrulline can be converted to arginine, which is a precursor for nitric oxide. Several proteins contain citrulline as a result of a posttranslational modification. These citrulline residues are generated by a family of enzymes called peptidylarginine deiminases (PADs), which convert arginine into citrulline in a process called citrullination or deimination. Proteins that normally contain citrulline residues include myelin basic protein (MBP), filaggrin, and several histone proteins, whereas other proteins, such as fibrin and vimentin are susceptible to citrullination during cell death and tissue inflammation.


DL-Citrulline (CAS 627-77-0) References

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  2. Conversion of citrulline to ornithine by pleuropneumonialike organisms.  |  SMITH, PF. 1957. J Bacteriol. 74: 801-6. PMID: 13502308
  3. Phosphorolysis of citrulline by mammalian liver; the effect of a bacterial activator.  |  KREBS, HA., et al. 1958. Biochem J. 70: 397-402. PMID: 13596356
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  5. Arsenolysis and phosphorolysis of citrulline in mammalian liver.  |  KREBS, HA., et al. 1955. Biochem J. 59: 185-93. PMID: 14351178
  6. METABOLIC CHARACTERIZATION OF THE GENUS BRUCELLA IV. 3: Correlation of Oxidative Metabolic Patterns and Susceptibility to Brucella Bacteriophage, Type abortus, Strain.  |  Meyer, ME. 1961. J Bacteriol. 82: 950-3. PMID: 16561925
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  8. Detection of Vaginal Metabolite Changes in Premature Rupture of Membrane Patients in Third Trimester Pregnancy: a Prospective Cohort Study.  |  Liu, L., et al. 2021. Reprod Sci. 28: 585-594. PMID: 33025530
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  11. Optimization of conditions for the colorimetric determination of citrulline, using diacetyl monoxime.  |  Boyde, TR. and Rahmatullah, M. 1980. Anal Biochem. 107: 424-31. PMID: 7435971
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  13. GC–MS analysis of Polycarpaea corymbosa (L.) Lam whole plant  |  Balamurugan, K., Nishanthini, A., & Mohan, V. R. 2012. Asian Pacific Journal of Tropical Biomedicine. 2(3): S1289-S1292.

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

DL-Citrulline, 5 g

sc-268966
5 g
$150.00