Date published: 2025-12-3

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DL-α-(Difluoromethyl)arginine (CAS 69955-43-7)

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Alternate Names:
n5-(diaminomethylidene)-2-(difluoromethyl)ornithine
Application:
DL-α-(Difluoromethyl)arginine is A compound employed in plant growth regulation
CAS Number:
69955-43-7
Purity:
98%
Molecular Weight:
224.21
Molecular Formula:
C7H14F2N4O2
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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DL-α-(Difluoromethyl)arginine is employed in plant growth regulation. DL-α-(Difluoromethyl)arginine is a synthetic amino acid derivative derived from L-arginine, a naturally occurring amino acid. It has been extensively used in scientific research for multiple purposes. Additionally, it has been utilized in investigations of cell signaling pathways, particularly in understanding the role of nitric oxide in cell signaling. The primary mechanism of DL-α-(Difluoromethyl)arginine involves inhibiting nitric oxide synthase (NOS), the enzyme responsible for nitric oxide production. By impeding NOS, this compound reduces the generation of nitric oxide, consequently impacting numerous biochemical and physiological processes. Notably, the inhibition of NOS by DL-α-(Difluoromethyl)arginine can lead to decreased vasodilation and increased blood pressure, as it affects the production of nitric oxide. Moreover, this inhibition can influence the production of other molecules such as cyclic GMP and cyclic AMP, resulting in diminished cell proliferation and apoptosis.


DL-α-(Difluoromethyl)arginine (CAS 69955-43-7) References

  1. A Plant Pathogen Type III Effector Protein Subverts Translational Regulation to Boost Host Polyamine Levels.  |  Wu, D., et al. 2019. Cell Host Microbe. 26: 638-649.e5. PMID: 31628081
  2. BrrICE1.1 is associated with putrescine synthesis through regulation of the arginine decarboxylase gene in freezing tolerance of turnip (Brassica rapa var. rapa).  |  Yin, X., et al. 2020. BMC Plant Biol. 20: 504. PMID: 33148172
  3. Piriformospora indica recruits host-derived putrescine for growth promotion in plants.  |  Kundu, A., et al. 2022. Plant Physiol. 188: 2289-2307. PMID: 34791442
  4. DL-alpha-(Difluoromethyl)arginine: a potent enzyme-activated irreversible inhibitor of bacterial decarboxylases.  |  Kallio, A., et al. 1981. Biochemistry. 20: 3163-8. PMID: 6788079
  5. Polyamine biosynthesis in Cryptosporidium parvum and its implications for chemotherapy.  |  Keithly, JS., et al. 1997. Mol Biochem Parasitol. 88: 35-42. PMID: 9274865

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

DL-α-(Difluoromethyl)arginine, 10 mg

sc-211368A
10 mg
$265.00

DL-α-(Difluoromethyl)arginine, 25 mg

sc-211368
25 mg
$347.00

DL-α-(Difluoromethyl)arginine, 250 mg

sc-211368B
250 mg
$2448.00