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DL-5-Hydroxytryptophan (CAS 114-03-4)

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Alternate Names:
2-Amino-3-(5-Hydroxy-1H-Indol-3-Yl)Propanoic Acid
CAS Number:
114-03-4
Molecular Weight:
220.23
Molecular Formula:
C11H12N2O3
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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DL-5-Hydroxytryptophan is frequently used in biochemical research to study its role as a precursor in the biosynthesis of serotonin, a critical neurotransmitter. This compound is instrumental in understanding the enzymatic pathways and metabolic processes involved in serotonin production. Researchers utilize DL-5-Hydroxytryptophan to explore the regulation of serotonin levels in various model organisms, providing insights into the mechanisms that influence mood, behavior, and neurological function. Additionally, this chemical is used in the study of metabolic disorders related to neurotransmitter imbalances, aiding in the elucidation of biochemical pathways. DL-5-Hydroxytryptophan also serves as a tool in genetic studies, where it helps identify genes involved in serotonin metabolism and its related biological pathways.


DL-5-Hydroxytryptophan (CAS 114-03-4) References

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  2. The oxytocic activity of DL-5-hydroxytryptophan.  |  LOVASEN, Z., et al. 1961. J Pharm Pharmacol. 13: 565-6. PMID: 13763752
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  5. dl-Fenfluramine inhibits ethanol-induced ascorbic acid release in rat striatum studied by microdialysis.  |  Chun-Fu, WU., et al. 1998. Addict Biol. 3: 295-308. PMID: 26734923
  6. The effects of DL-5-hydroxytryptophan on ethanol consumption by rats.  |  Zabik, JE., et al. 1978. Res Commun Chem Pathol Pharmacol. 20: 69-78. PMID: 307265
  7. First characterization of 5-hydroxytryptophan in rat brain by using specific antibodies.  |  Geffard, M., et al. 1987. Brain Res. 426: 191-6. PMID: 3121135
  8. Effect of 5-hydroxytryptophan on H-reflex recovery curves in normal subjects and patients with affective disorders.  |  Metz, JT., et al. 1988. Biol Psychiatry. 23: 602-11. PMID: 3128339
  9. Studies on DL-5-hydroxytryptophan-induced hyperactivity in mice.  |  Modigh, K. 1974. Adv Biochem Psychopharmacol. 10: 213-7. PMID: 4546515
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  11. Product induction in Pseudomonas acidovorans of a permease system which transports L-tryptophan.  |  Rosenfeld, H. and Feigelson, P. 1969. J Bacteriol. 97: 705-14. PMID: 5773025
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  13. 5-HT antagonists suppress sleep and delay its restoration after 5-HTP in p-chlorophenylalanine-pretreated cats.  |  Sallanon, M., et al. 1982. Eur J Pharmacol. 82: 29-35. PMID: 6215254
  14. The effect of DL-5-hydroxytryptophan (5-HTP) on plasma prolactin in pituitary stalk sectioned rats.  |  Akabori, A., et al. 1981. Endocrinol Jpn. 28: 541-5. PMID: 6985126

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

DL-5-Hydroxytryptophan, 1 g

sc-471344
1 g
$62.00