
DJ-1 Antibody (mαDJ-1/E2-29) is a mouse monoclonal IgM antibody that detects DJ-1 in human samples through applications such as western blotting (WB), immunoprecipitation (IP), and immunofluorescence (IF). DJ-1 is a highly-conserved protein that plays a crucial role in cellular processes, particularly in protecting cells from oxidative stress and maintaining mitochondrial function. DJ-1 regulates the androgen receptor by forming a complex with PIASxα, highlighting its importance in various signaling pathways, which can influence cell growth and survival. DJ-1 is predominantly located in the cytoplasm but translocates to the nucleus during the S phase of the cell cycle, indicating involvement in cell cycle regulation and response to growth stimuli. Mutations in the DJ-1 gene have been linked to neurodegenerative diseases, including Parkinson′s disease, underscoring the significance of DJ-1 in neuronal health. The gene encoding human DJ-1 is located on chromosome 1p36.23, a region associated with chromosomal abnormalities in several tumors, further emphasizing DJ-1′s relevance in cancer biology. Anti-DJ-1 antibody (mαDJ-1/E2-29) is an essential tool for researchers studying the multifaceted roles of DJ-1 in health and disease.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
DJ-1 Antibody (mαDJ-1/E2-29) | sc-33665 | 200 µg/ml | $322.00 | |||
DJ-1 Antibody (mαDJ-1/E2-29): m-IgGκ BP-HRP Bundle | sc-551929 | 200 µg Ab; 40 µg BP | $361.00 |