Disopyramide Antibody (004): sc-66035

Disopyramide Antibody (004) is a mouse monoclonal IgG2b antibody that detects Disopyramide in non-species reactive samples by enzyme-linked immunosorbent assay (ELISA). Disopyramide is a Class IA antiarrhythmic medication that plays a crucial role in managing ventricular and supraventricular arrhythmias, particularly following heart attacks. Disopyramide (004) antibody recognizes a protein that stabilizes irregular heartbeats by directly interfering with the depolarization of the cardiac membrane, acting as a membrane-stabilizing agent. This mechanism is essential for maintaining normal heart rhythm, as Disopyramide shortens the sinus node recovery time and lengthens the effective refractory period of the atrium, while minimally affecting the effective refractory period of the atrioventricular node. Additionally, Disopyramide exhibits depressant actions on the heart akin to guanidine and possesses anticholinergic and local anesthetic properties, which can contribute to therapeutic effects. Common side effects include dizziness, feelings of faintness, dry mouth, heartbeat sensations, shortness of breath, and unusual tiredness, which may arise during treatment. Anti-Disopyramide antibody (004) serves as an invaluable tool for researchers studying the pharmacological effects and mechanisms of this important antiarrhythmic agent.