Molecular structure of Dioleoylglycerol, CAS Number: 25637-84-7
Dioleoylglycerol (CAS 25637-84-7)
Alternate Names:
Diolein; Glycerol-1,2- and -1,3-dioleate
CAS Number:
25637-84-7
Purity:
≥98%
Molecular Weight:
620.99
Molecular Formula:
C39H72O5
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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Dioleoylglycerol is a lipid molecule that functions as a substrate in lipid metabolism studies. It is used to investigate the enzymatic activity of lipases and other lipid-modifying enzymes. Dioleoylglycerol serves as a model compound for studying the hydrolysis and synthesis of triglycerides in cellular and biochemical processes. Its mechanism of action involves serving as a precursor for the synthesis of other lipid molecules, and it can also act as a signaling molecule in lipid-mediated cellular pathways.
Dioleoylglycerol (CAS 25637-84-7) References
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- Pancreatic amylase secretion and cytoplasmic free calcium. Effects of ionomycin, phorbol dibutyrate and diacylglycerols alone and in combination. | Merritt, JE. and Rubin, RP. 1985. Biochem J. 230: 151-9. PMID: 2413839
- Phenol esterase activity of porcine skin. | Laszlo, JA., et al. 2015. Eur J Pharm Biopharm. 89: 175-81. PMID: 25497179
- Eicosapentaenoic acid reduces hepatic synthesis and secretion of triacylglycerol by decreasing the activity of acyl-coenzyme A:1,2-diacylglycerol acyltransferase. | Rustan, AC., et al. 1988. J Lipid Res. 29: 1417-26. PMID: 2853717
- Structural Identification and Systematic Comparison of Phorbol Ester, Dioleoylglycerol, Alcohol and Sevoflurane Binding Sites in PKCδ C1A Domain. | Shi, L. 2018. Protein J. 37: 539-547. PMID: 30251087
- Integral Stereoselectivity of Lipase Based on the Chromatographic Resolution of Enantiomeric/Regioisomeric Diacylglycerols. | Choi, Y., et al. 2021. J Agric Food Chem. 69: 325-331. PMID: 33397094
- Lysolipids regulate raft size distribution. | Krasnobaev, VD., et al. 2022. Front Mol Biosci. 9: 1021321. PMID: 36275621
- Hormone-sensitive lipase and monoacylglycerol lipase are both required for complete degradation of adipocyte triacylglycerol. | Fredrikson, G., et al. 1986. Biochim Biophys Acta. 876: 288-93. PMID: 3955067
- Affinity chromatography of human adipose tissue triacylglycerol lipase on agarose-linked dioleoylglycerol. | Verine, A., et al. 1974. Biochim Biophys Acta. 369: 125-8. PMID: 4422493
- Effect of L-alpha-phosphatidylinositol on a vascular smooth muscle Ca2+-dependent protease. Reduction of the Ca2+ requirement for autolysis. | Coolican, SA. and Hathaway, DR. 1984. J Biol Chem. 259: 11627-30. PMID: 6090440
- In vitro effect of adrenocorticotrophic hormone on the pH profile of tri- and diester lipase activities from rat brain. | Arnaud, J., et al. 1980. Biochim Biophys Acta. 617: 524-8. PMID: 6245706
- Properties of diacylglycerol kinase in adult and fetal rat lung. | Ide, H. and Weinhold, PA. 1982. Biochim Biophys Acta. 713: 547-54. PMID: 6295502
- Modulation by gangliosides of the lamellar-inverted micelle (hexagonal II) phase transition in mixtures containing phosphatidylethanolamine and dioleoylglycerol. | Perillo, MA., et al. 1994. Proc Natl Acad Sci U S A. 91: 10019-23. PMID: 7937830
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Dioleoylglycerol, 50 mg | sc-214904 | 50 mg | $72.00 | |||
Dioleoylglycerol, 100 mg | sc-214904A | 100 mg | $134.00 |