Date published: 2025-12-5

1-800-457-3801

SCBT Portrait Logo
Seach Input

Diethylsilane (CAS 542-91-6)

0.0(0)
Write a reviewAsk a question

Alternate Names:
3-Silapentane
CAS Number:
542-91-6
Molecular Weight:
88.22
Molecular Formula:
C4H12Si
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

QUICK LINKS

Diethylsilane is a reducing agent in various chemical reactions. It acts as a source of silicon in the synthesis of organosilicon compounds, participating in hydrosilylation reactions to form carbon-silicon bonds. Diethylsilane′s mechanism of action involves the transfer of a hydride ion to a substrate, facilitating the reduction of functional groups such as carbonyls and olefins. Diethylsilane plays a role in the production of silicon-containing materials and serves as a precursor in the preparation of silicon-based polymers and coatings. Diethylsilane interacts at the molecular level, participating in hydrosilylation reactions to modify the structure of organic compounds. Its function as a reducing agent allows for the manipulation of chemical structures and the synthesis of diverse silicon-containing compounds for development purposes.


Diethylsilane (CAS 542-91-6) References

  1. Solid-phase, Pd-catalyzed silicon-aryl carbon bond formation. Synthesis of sansalvamide A peptide.  |  Gu, W., et al. 2002. Org Lett. 4: 4171-4. PMID: 12423114
  2. DOTTADs--readily made novel metal ligands with multivariant functionality.  |  Arany, A., et al. 2003. Org Biomol Chem. 1: 1545-51. PMID: 12926285
  3. Dihydrogen Activation by Titanium Sulfide Complexes.  |  Sweeney, ZK., et al. 1999. Organometallics. 18: 5502-5510. PMID: 16633550
  4. Rotational spectra and conformational analysis of diethylsilane and diethyldifluorosilane.  |  Peebles, SA., et al. 2009. J Phys Chem A. 113: 3137-42. PMID: 19243160
  5. Development and mechanistic investigation of a highly efficient iridium(V) silyl complex for the reduction of tertiary amides to amines.  |  Park, S. and Brookhart, M. 2012. J Am Chem Soc. 134: 640-53. PMID: 22091749
  6. Iridium-catalyzed reduction of secondary amides to secondary amines and imines by diethylsilane.  |  Cheng, C. and Brookhart, M. 2012. J Am Chem Soc. 134: 11304-7. PMID: 22770123
  7. Metal-free deoxygenation of carbohydrates.  |  Adduci, LL., et al. 2014. Angew Chem Int Ed Engl. 53: 1646-9. PMID: 24492972
  8. Iridium-catalyzed regioselective silylation of secondary alkyl C-H bonds for the synthesis of 1,3-diols.  |  Li, B., et al. 2014. J Am Chem Soc. 136: 6586-9. PMID: 24734777
  9. Iridium-catalyzed regioselective silylation of aromatic and benzylic C-H bonds directed by a secondary amine.  |  Li, Q., et al. 2014. Angew Chem Int Ed Engl. 53: 8471-4. PMID: 24962972
  10. Rhodium-Catalyzed Enantioselective Silylation of Cyclopropyl C-H Bonds.  |  Lee, T. and Hartwig, JF. 2016. Angew Chem Int Ed Engl. 55: 8723-7. PMID: 27253898
  11. Rhodium-Catalyzed Regioselective Silylation of Alkyl C-H Bonds for the Synthesis of 1,4-Diols.  |  Karmel, C., et al. 2018. J Am Chem Soc. 140: 1460-1470. PMID: 29293327
  12. Cobalt-catalysed selective synthesis of aldehydes and alcohols from esters.  |  Pattanaik, S. and Gunanathan, C. 2020. Chem Commun (Camb). 56: 7345-7348. PMID: 32484179
  13. Catalyst- and Silane-Controlled Enantioselective Hydrofunctionalization of Alkenes by Cobalt-Catalyzed Hydrogen Atom Transfer and Radical-Polar Crossover.  |  Ebisawa, K., et al. 2020. J Am Chem Soc. 142: 13481-13490. PMID: 32648757

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Diethylsilane, 5 ml

sc-257346
5 ml
$77.00