Deoxy Blebbistatin (CAS 856925-72-9)
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Deoxy Blebbistatin, as a derivative of Blebbistatin, acts as a potent inhibitor of myosin II, a motor protein essential for various cellular processes, including cytokinesis, cell motility, and the maintenance of cell shape. By specifically targeting and inhibiting the ATPase activity of myosin II, Deoxy Blebbistatin effectively blocks the myosin II-dependent processes by preventing the conformational changes required for myosin′s interaction with actin filaments. This inhibition disrupts the contractile mechanisms central to cell movement and division, making Deoxy Blebbistatin useful in the study of cellular mechanics and the role of myosin II in cell motility, morphogenesis, and division. In research applications, this compound allows scientists to probe the fundamental aspects of cell behavior and understand the molecular basis of myosin II′s contribution to the dynamic remodeling of the cytoskeleton.
Deoxy Blebbistatin (CAS 856925-72-9) References
- Dissecting temporal and spatial control of cytokinesis with a myosin II Inhibitor. | Straight, AF., et al. 2003. Science. 299: 1743-7. PMID: 12637748
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Deoxy Blebbistatin, 25 mg | sc-218116 | 25 mg | $312.00 |