DBCO-PEG5-NHS ester (CAS 1378531-80-6)
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DBCO-PEG5-NHS ester is a PEG analog equipped with NHS ester functionality, enabling it to selectively and effectively react with primary amines under neutral or slightly basic conditions. This reaction results in the formation of a stable covalent bond, particularly with lysine residues or aminosilane-coated surfaces. The incorporation of a hydrophilic PEG spacer arm not only enhances water solubility but also serves as a lengthy and flexible connector, mitigating steric hindrance during the ligation process. DBCO-PEG5-NHS ester is used in bioconjugation. The DBCO moiety allows for efficient and specific linking of molecules without affecting the biological activity of sensitive biomolecules. DBCO-PEG5-NHS ester enables the site-specific modification of biomolecules with various functional groups, including fluorescent dyes and targeting ligands, without the need for complex chemical conditions or catalysts.
DBCO-PEG5-NHS ester (CAS 1378531-80-6) References
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Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
DBCO-PEG5-NHS ester, 10 mg | sc-499348 | 10 mg | $186.00 | |||
DBCO-PEG5-NHS ester, 25 mg | sc-499348A | 25 mg | $374.00 | |||
DBCO-PEG5-NHS ester, 100 mg | sc-499348B | 100 mg | $823.00 | |||
DBCO-PEG5-NHS ester, 500 mg | sc-499348C | 500 mg | $2611.00 |