Collagen I is the most abundant type of collagen found in vertebrates and is central to the structure and function of various connective tissues, including skin, bone, tendon, and ligaments. In scientific research, Collagen I is extensively utilized for its biocompatibility, bioactivity, and structural properties, crucial for studying cell behavior and tissue engineering. Molecularly, Collagen I consists of three polypeptide chains that form a triple helix structure, imparting high tensile strength to tissues. This feature is leveraged in research to create scaffolds that mimic the natural extracellular matrix, facilitating the study of cell migration, proliferation, and differentiation in conditions that closely resemble natural environments. Collagen I is commonly used in vitro to explore cellular interactions with the extracellular matrix. By coating culture dishes with Collagen I, researchers can observe how cells attach, spread, and organize, which is essential for understanding processes such as wound healing and tissue regeneration. Furthermore, the application of Collagen I in 3D culture systems provides a more physiologically relevant model to study the architectural and mechanical properties of tissues.
Ordering Information
Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Collagen I, rat tail (3-5 mg/ml) | sc-136157 | 100 mg | $306.00 |