Climbazole-d4 (CAS 1185117-79-6)
QUICK LINKS
Climbazole-d4, a novel synthetic molecule, holds vast potential for scientific research applications. Derived from the widely utilized antimycotic drug Climbazole, it serves as a research tool to investigate the effects of Climbazole in various scientific experiments. Climbazole-d4 has been extensively employed in diverse research studies, enabling the examination of Climbazole′s impact on fungal growth, gene expression, protein structure and function, as well as secondary metabolite production. The precise mechanism of action for Climbazole-d4 remains partially understood however, it is hypothesized to inhibit fungal growth by disrupting the cell wall and impeding the synthesis of ergosterol, a component of fungal cell membranes. Additionally, it is believed to influence the expression of specific genes associated with fungal growth and development. Serving as a labeled form of Climbazole, Climbazole-d4 acts as an imidazole antifungal agent. When incorporated into shampoo formulations, it provides beneficial effects in combating dandruff.
Climbazole-d4 (CAS 1185117-79-6) References
- Ecotoxicity of climbazole, a fungicide contained in antidandruff shampoo. | Richter, E., et al. 2013. Environ Toxicol Chem. 32: 2816-25. PMID: 23982925
- Effects of antimicrobial exposure on detrital biofilm metabolism in urban and rural stream environments. | Jepsen, R., et al. 2019. Sci Total Environ. 666: 1151-1160. PMID: 30970480
- Comparison of high resolution mrm and sequential window acquisition of all theoretical fragment-ion acquisition modes for the quantitation of 48 wastewater-borne pollutants in lettuce. | Montemurro, N., et al. 2020. J Chromatogr A. 1631: 461566. PMID: 33002708
- Ecotoxicological risk assessment of wastewater irrigation on soil microorganisms: Fate and impact of wastewater-borne micropollutants in lettuce-soil system. | Gallego, S., et al. 2021. Ecotoxicol Environ Saf. 223: 112595. PMID: 34390984
- One-step extraction and analysis of 45 contaminants of emerging concern using QuEChERS methodology and HR-MS in radish leaves and roots. | Labad, F., et al. 2021. MethodsX. 8: 101308. PMID: 34434828
- Passive sampling and in vitro assays to monitor antiandrogens in a river affected by wastewater discharge. | Elkayar, K., et al. 2022. Sci Total Environ. 804: 150067. PMID: 34509830
- Solid-phase extraction and fractionation of multiclass pollutants from wastewater followed by liquid chromatography tandem-mass spectrometry analysis. | Fernández-Fernández, V., et al. 2022. Anal Bioanal Chem. 414: 4149-4165. PMID: 35461386
- Basic micro-pollutants in sludge from municipal wastewater treatment plants in the Northwest Spain: Occurrence and risk assessment of sludge disposal. | Fernández-Fernández, V., et al. 2023. Chemosphere. 335: 139094. PMID: 37268235
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Climbazole-d4, 1 mg | sc-217928 | 1 mg | $347.00 |