Date published: 2025-12-10

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cis-3-Azabicyclo[3.1.0]hexane-2-carboxylic acid (CAS 33294-81-4)

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Alternate Names:
(1R,2S,5S)-3-azabicyclo[3.1.0]hexane-2-carboxylic acid
CAS Number:
33294-81-4
Molecular Weight:
127.14
Molecular Formula:
C6H9NO2
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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cis-3-Azabicyclo[3.1.0]hexane-2-carboxylic acid is a synthetic compound that is of particular interest in the field of organic chemistry for its rigid bicyclic structure, which provides a constrained framework for the study of conformational dynamics in small molecules. Its azabicyclic core is structurally analogous to certain amino acids and as such, is useful in probing the role of ring strain and stereochemistry in biological systems. Research involving cis-3-Azabicyclo[3.1.0]hexane-2-carboxylic acid often focuses on the synthesis of novel compounds and peptidomimetics, where its conformationally restricted backbone can mimic the secondary structures of peptides. The compound is also employed in the development of enzyme inhibitors, where the cis configuration of the carboxylic acid group is for the molecular recognition and binding processes. Additionally, cis-3-Azabicyclo[3.1.0]hexane-2-carboxylic acid serves as a scaffold in the design of new materials with potential applications in catalysis and molecular recognition.


cis-3-Azabicyclo[3.1.0]hexane-2-carboxylic acid (CAS 33294-81-4) References

  1. Substrate specificity of the amino acid transporter PAT1.  |  Metzner, L., et al. 2006. Amino Acids. 31: 111-7. PMID: 16699824

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

cis-3-Azabicyclo[3.1.0]hexane-2-carboxylic acid, 250 mg

sc-227662
250 mg
$148.00