Date published: 2026-5-16

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Chlorotriphenylsilane (CAS 76-86-8)

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Alternate Names:
Triphenylchlorosilane; TPSCl; Triphenylsilyl chloride
CAS Number:
76-86-8
Molecular Weight:
294.8
Molecular Formula:
C18H15ClSi
Supplemental Information:
This is as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Chlorotriphenylsilane, often utilized in the realm of synthetic organic chemistry, plays a pivotal role as a reagent in the introduction of phenyl groups into various molecular frameworks. Its mechanism of action is rooted in its ability to undergo nucleophilic substitution reactions, where the chloro group is replaced by nucleophiles, thus facilitating the formation of diverse organosilicon compounds. This capacity makes it an invaluable tool in the synthesis of complex organic molecules, enabling researchers to tailor the physicochemical properties of these molecules for specific applications. Additionally, chlorotriphenylsilane serves as a stepping stone in the creation of cross-coupling reagents and silicon-based protecting groups, further underscoring its significance in the advancement of organic synthesis methodologies. Its role extends beyond mere functionalization, as it aids in the strategic manipulation of molecular architecture, thereby contributing to the exploration and development of novel compounds with potential utility in various research domains.


Chlorotriphenylsilane (CAS 76-86-8) References

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  6. Unintentional PCB in chlorophenylsilanes as a source of contamination in environmental samples.  |  Anezaki, K. and Nakano, T. 2015. J Hazard Mater. 287: 111-7. PMID: 25634145
  7. Transition-Metal-Free Cross-Coupling of Benzothiophenes and Styrenes in a Stereoselective Synthesis of Substituted (E,Z)-1,3-Dienes.  |  Šiaučiulis, M., et al. 2019. Angew Chem Int Ed Engl. 58: 8779-8783. PMID: 30964596
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  12. Cyano(triphenylsilyl)phosphanide as a Building Block for P,C,N Conjugated Molecules.  |  Le Corre, G., et al. 2021. Angew Chem Int Ed Engl. 60: 24817-24822. PMID: 34463413
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Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Chlorotriphenylsilane, 5 g

sc-239538
5 g
$21.00