Date published: 2026-6-19

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Chlorotriisobutylsilane (CAS 13154-25-1)

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Alternate Names:
Triisobutylchlorosilane, Triisobutylsilyl chloride
CAS Number:
13154-25-1
Molecular Weight:
234.88
Molecular Formula:
C12H27ClSi
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
Available in US only.
* Refer to Certificate of Analysis for lot specific data.

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Chlorotriisobutylsilane functions as a silylating agent in chemical reactions. It is used to introduce trimethylsilyl groups to various organic compounds, facilitating their analysis by gas chromatography-mass spectrometry. The mechanism of action of chlorotriisobutylsilane involves the substitution of hydrogen atoms with trimethylsilyl groups, leading to the formation of silyl derivatives. This process occurs through the reaction of the chlorine atom in the compound with the hydrogen atom in the organic molecule, resulting in the release of hydrogen chloride and the attachment of the trimethylsilyl group. This silylation reaction enables the enhancement of the volatility and thermal stability of the organic compounds, allowing for their efficient analysis and characterization in research and development applications.


Chlorotriisobutylsilane (CAS 13154-25-1) References

  1. Arginine-rich peptides are blockers of VR-1 channels with analgesic activity.  |  Planells-Cases, R., et al. 2000. FEBS Lett. 481: 131-6. PMID: 10996311
  2. Stereocontrolled synthesis and cycloaddition of 1,2,4-trioxygenated 1,3-dienes.  |  Pichon, N., et al. 2006. J Org Chem. 71: 1892-901. PMID: 16496973
  3. Tailor-made additives for morphology control in molecular bulk-heterojunction photovoltaics.  |  Graham, KR., et al. 2013. ACS Appl Mater Interfaces. 5: 63-71. PMID: 23206429

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Chlorotriisobutylsilane, 5 g

sc-227640
5 g
$148.00
US: Only available in the US