Molecular structure of Chloromethyl methyl sulfide, CAS Number: 2373-51-5
Chloromethyl methyl sulfide (CAS 2373-51-5)
Application:
Chloromethyl methyl sulfide is a methylene transfer reagent for iron(II) mediated cyclopropanation
CAS Number:
2373-51-5
Purity:
95%
Molecular Weight:
96.58
Molecular Formula:
CH3SCH2Cl
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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Description
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SDS & Certificate of Analysis
Chloromethyl methyl sulfide is methylene transfer reagent for iron(II) mediated cyclopropanation and methylthiomethylating reagent for carbonyl and aromatic compounds. Highly reactive, especially with nitrogen bases and sulfur nucleophiles. Toxic effects are due to its alkynation ability on DNA, RNA, and proteins which leads to cell death.
Chloromethyl methyl sulfide (CAS 2373-51-5) References
- Combination of betulinic acid with diazen-1-ium-1,2-diolate nitric oxide moiety donating a novel anticancer candidate. | Zhang, L., et al. 2018. Onco Targets Ther. 11: 361-373. PMID: 29391813
- Practical Glucosylations and Mannosylations Using Anomeric Benzoyloxy as a Leaving Group Activated by Sulfonium Ion. | Xing, L., et al. 2017. ACS Omega. 2: 3698-3709. PMID: 30023701
- A 5 + 1 Protic Acid Assisted Aza-Pummerer Approach for Synthesis of 4-Chloropiperidines from Homoallylic Amines. | Ebule, R., et al. 2019. J Org Chem. 84: 3249-3259. PMID: 30758961
- Mild, Selective Sulfoxidation with Molybdenum(VI) cis-Dioxo Catalysts. | Cantwell, KE., et al. 2017. ACS Omega. 2: 1778-1785. PMID: 31457541
- Transcriptome and phytochemical analyses provide insights into the organic sulfur pathway in Allium hirtifolium. | Soorni, A., et al. 2021. Sci Rep. 11: 768. PMID: 33436989
- A Convenient Protecting Group for Uridine Ureido Nitrogen: (4,4'-Bisfluorophenyl)methoxymethyl group. | Mitachi, K., et al. 2021. Synthesis (Stuttg). 53: 2643-2650. PMID: 35431351
- One-Pot Reductive Methylation of Nitro- and Amino-Substituted (Hetero)Aromatics with DMSO/HCOOH: Concise Synthesis of Fluorescent Dimethylamino-Functionalized Bibenzothiazole Ligands with Tunable Emission Color upon Complexation. | Osuský, P., et al. 2022. J Org Chem. 87: 10613-10629. PMID: 35917477
- Autocatalytic methylthiomethylation of carboxylic acid/phenol involving the formation of DMSO enolate: convenient synthesis of methylthiomethyl ester/ether. | Liu, H., et al. 2022. RSC Adv. 12: 33156-33159. PMID: 36425198
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Chloromethyl methyl sulfide, 5 g | sc-252589 | 5 g | $39.00 | |||
Chloromethyl methyl sulfide, 25 g | sc-252589A | 25 g | $122.00 |