Date published: 2026-4-30

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Chloroiodoacetic acid (CAS 53715-09-6)

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Alternate Names:
2-Chloro-2-iodoacetic acid
CAS Number:
53715-09-6
Molecular Weight:
220.39
Molecular Formula:
C2H2ClIO2
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Chloroiodoacetic acid, a compound consisting of chlorine, iodine, and acetic acid, is a colorless crystalline solid emitting a pungent odor. Its utility extends across various domains, including pharmaceutical synthesis, chemical production, and scientific investigations. This versatile compound finds application in the synthesis of pharmaceuticals, polymers, dyes, and diverse materials. Moreover, it has been employed in scientific research to explore gene expression, enzyme functionality, and other intricate biochemical processes.


Chloroiodoacetic acid (CAS 53715-09-6) References

  1. Determination of iodoacetic acid using liquid chromatography/electrospray tandem mass spectrometry.  |  Lau, BP. and Becalski, A. 2008. Rapid Commun Mass Spectrom. 22: 1787-91. PMID: 18470871
  2. Rapid IC-ICP/MS method for simultaneous analysis of iodoacetic acids, bromoacetic acids, bromate, and other related halogenated compounds in water.  |  Shi, H. and Adams, C. 2009. Talanta. 79: 523-7. PMID: 19559915
  3. A picture of polar iodinated disinfection byproducts in drinking water by (UPLC/)ESI-tqMS.  |  Ding, G. and Zhang, X. 2009. Environ Sci Technol. 43: 9287-93. PMID: 20000522
  4. Analysis of iodinated haloacetic acids in drinking water by reversed-phase liquid chromatography/electrospray ionization/tandem mass spectrometry with large volume direct aqueous injection.  |  Li, Y., et al. 2012. J Chromatogr A. 1245: 75-82. PMID: 22658134
  5. Identification, toxicity and control of iodinated disinfection byproducts in cooking with simulated chlor(am)inated tap water and iodized table salt.  |  Pan, Y., et al. 2016. Water Res. 88: 60-68. PMID: 26474150
  6. Formation and occurrence of new polar iodinated disinfection byproducts in drinking water.  |  Pan, Y., et al. 2016. Chemosphere. 144: 2312-20. PMID: 26606185
  7. Analysis of haloacetic acids, bromate, and dalapon in natural waters by ion chromatography-tandem mass spectrometry.  |  Wu, S., et al. 2017. J Chromatogr A. 1487: 100-107. PMID: 28118976
  8. Formation of iodo-trihalomethanes, iodo-haloacetic acids, and haloacetaldehydes during chlorination and chloramination of iodine containing waters in laboratory controlled reactions.  |  Postigo, C., et al. 2017. J Environ Sci (China). 58: 127-134. PMID: 28774601
  9. Suspect screening of halogenated carboxylic acids in drinking water using ion exchange chromatography - high resolution (Orbitrap) mass spectrometry (IC-HRMS).  |  Gallidabino, MD., et al. 2018. Talanta. 178: 57-68. PMID: 29136864
  10. The stability of chlorinated, brominated, and iodinated haloacetamides in drinking water.  |  Ding, S., et al. 2018. Water Res. 142: 490-500. PMID: 29920459
  11. Chlorination of Source Water Containing Iodinated X-ray Contrast Media: Mutagenicity and Identification of New Iodinated Disinfection Byproducts.  |  Postigo, C., et al. 2018. Environ Sci Technol. 52: 13047-13056. PMID: 30339747
  12. Making Swimming Pools Safer: Does Copper-Silver Ionization with Chlorine Lower the Toxicity and Disinfection Byproduct Formation?  |  Allen, JM., et al. 2021. Environ Sci Technol. 55: 2908-2918. PMID: 33594894
  13. Are Disinfection Byproducts (DBPs) Formed in My Cup of Tea? Regulated, Priority, and Unknown DBPs.  |  Li, J., et al. 2021. Environ Sci Technol. 55: 12994-13004. PMID: 34523331
  14. Microseira wollei and Phormidium algae more than doubles DBP concentrations and calculated toxicity in drinking water.  |  Aziz, MT., et al. 2022. Water Res. 216: 118316. PMID: 35367941
  15. Do DBPs swim in salt water pools? Comparison of 60 DBPs formed by electrochemically generated chlorine vs. conventional chlorine.  |  Granger, CO. and Richardson, SD. 2022. J Environ Sci (China). 117: 232-241. PMID: 35725075

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Chloroiodoacetic acid, 5 mg

sc-471178
5 mg
$374.00

Chloroiodoacetic acid, 50 mg

sc-471178A
50 mg
$3131.00