Molecular structure of Cefalonium, CAS Number: 5575-21-3
Cefalonium (CAS 5575-21-3)
Application:
Cefalonium is a first generation cephalosporin antibiotic
CAS Number:
5575-21-3
Molecular Weight:
458.51
Molecular Formula:
C20H18N4O5S2
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
QUICK LINKS
Ordering Information
Description
Technical Information
Safety Information
SDS & Certificate of Analysis
Cefalonium, a cephalosporin antibiotic, demonstrates effectiveness against a collection of S. aureus strains obtained from the milk of lactating dairy cows experiencing mastitis, with a minimum inhibitory concentration of 2 µg/ml. Cefalonium, classified as a first-generation cephalosporin antibiotic, exhibits activity against aerobic gram-positive bacteria and certain gram-negative bacteria acquired within communities. The name for cefalonium is (6R,7R)-3-[(4-carbamoyl-1-pyridin-1-iumyl)methyl]-8-oxo-7-[(1-oxo-2-thiophen-2-ylethyl)amino]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate. Cefalonium hydrate belongs to the cephalosporin family.
Cefalonium (CAS 5575-21-3) References
- The intramammary efficacy of first generation cephalosporins against Staphylococcus aureus mastitis in mice. | Demon, D., et al. 2012. Vet Microbiol. 160: 141-50. PMID: 22677480
- A survey of antimicrobial usage on dairy farms and waste milk feeding practices in England and Wales. | Brunton, LA., et al. 2012. Vet Rec. 171: 296. PMID: 22903925
- Development of a rapid multi-residue assay for detecting β-lactams using penicillin binding protein 2x*. | Zeng, K., et al. 2013. Biomed Environ Sci. 26: 100-9. PMID: 23336133
- Evaluation of the Charm maximum residue limit β-lactam and tetracycline test for the detection of antibiotics in ewe and goat milk. | Beltrán, MC., et al. 2013. J Dairy Sci. 96: 2737-45. PMID: 23453521
- Development and validation of an ultra high performance liquid chromatography tandem mass spectrometry method for determination of 10 cephalosporins and desacetylcefapirin in milk. | Hou, XL., et al. 2013. J Chromatogr B Analyt Technol Biomed Life Sci. 931: 6-11. PMID: 23747425
- Susceptibility to cephalosporins of bacteria causing intramammary infections in dairy cows with a high somatic cell count in Germany. | Wente, N., et al. 2016. Prev Vet Med. 131: 146-151. PMID: 27401227
- Development and validation of a quantitative confirmatory method for 30 β-lactam antibiotics in bovine muscle using liquid chromatography coupled to tandem mass spectrometry. | Di Rocco, M., et al. 2017. J Chromatogr A. 1500: 121-135. PMID: 28449875
- Identification and determination of related substances of ceftaroline fosamil in medicinal product by high performance liquid chromatography with diode array detection and tandem mass spectrometry. | Karpiuk, I., et al. 2017. J Pharm Biomed Anal. 145: 651-660. PMID: 28800526
- Assessment of the Usefulness of Cefapirin and Cefalonium Disks for Susceptibility Testing of Staphylococcus aureus Isolates from Bovine Mastitis. | Harada, K., et al. 2020. Antibiotics (Basel). 9: PMID: 32326215
- Internal Teat Sealant Administered at Drying off Reduces Intramammary Infections during the Dry and Early Lactation Periods of Dairy Cows. | Freu, G., et al. 2020. Animals (Basel). 10: PMID: 32872097
- Anti-Metatype Antibody Screening, Sandwich Immunoassay Development, and Structural Insights for β-Lactams Based on Penicillin Binding Protein. | Bai, Y., et al. 2021. Molecules. 26: PMID: 34577037
- Identification and quantification of multi-class veterinary drugs and their metabolites in beef using LC-MS/MS. | Jung, YS., et al. 2022. Food Chem. 382: 132313. PMID: 35158273
- Development of a Quantitative Method for Detection of Multiclass Veterinary Drugs in Feed Using Modified QuPPe Extraction and LC-MS/MS. | Jang, S., et al. 2022. Molecules. 27: PMID: 35889354
- Potential of ESBL-producing Escherichia coli selection in bovine feces after intramammary administration of first generation cephalosporins using in vitro experiments. | Speksnijder, DC., et al. 2022. Sci Rep. 12: 15083. PMID: 36065056
- Analysis of Antimicrobials in Muscle and Drinking Water in Terms of Reducing the Need of Antimicrobial Use by Increasing the Health and Welfare of Pig and Broiler. | Gajda, A., et al. 2023. Antibiotics (Basel). 12: PMID: 36830237
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Cefalonium, 100 mg | sc-300330 | 100 mg | $215.00 | |||
Cefalonium, 250 mg | sc-300330A | 250 mg | $430.00 |