CDV envelope antigen Antibody (7515): sc-58104

CDV envelope antigen Antibody (7515) is a mouse monoclonal IgG2a antibody that detects the envelope antigen of Canine Distemper Virus (CDV) by enzyme-linked immunosorbent assay (ELISA). Anti-CDV envelope antigen antibody (7515) is available in a non-conjugated form, specifically designed for the detection of CDV envelope antigen. Canine distemper is a highly infectious viral disease caused by the Morbillivirus genus, significantly impacting the respiratory, gastrointestinal, and central nervous systems of dogs and other carnivores, with young dogs aged four months to four years being particularly vulnerable. The envelope protein of CDV plays a crucial role in virus infection of host cells, facilitating fusion of the viral membrane with the host cell membrane, allowing viral genome entry and replication initiation. This process drives disease pathogenesis, leading to severe neurological complications and, in many cases, death. Understanding envelope protein function remains essential for developing effective vaccines and therapeutic strategies against CDV, as this protein serves as a key target for neutralizing antibodies.

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CDV envelope antigen Antibody (7515) References:

1. DNA vaccine encoding nucleocapsid and surface proteins of wild type canine distemper virus protects its natural host against distemper.  |  Cherpillod, P., et al. 2000. Vaccine. 18: 2927-36. PMID: 10825593
2. Canine distemper virus in seals.  |  Osterhaus, AD., et al. 1988. Nature. 335: 403-4. PMID: 3419515
3. Canine distemper virus: review of structural and functional modulations in lymphoid tissues.  |  Krakowka, S., et al. 1980. Am J Vet Res. 41: 284-92. PMID: 6989302
4. Demyelination in experimental canine distemper virus infection: immunological, pathologic, and immunohistological studies.  |  Vandevelde, M., et al. 1982. Acta Neuropathol. 56: 285-93. PMID: 7090737
5. Detection of canine distemper virus nucleocapsid protein gene in canine peripheral blood mononuclear cells by RT-PCR.  |  Shin, Y., et al. 1995. J Vet Med Sci. 57: 439-45. PMID: 7548395
6. Aspects of canine distemper virus and measles virus encephalomyelitis.  |  Summers, BA. and Appel, MJ. 1994. Neuropathol Appl Neurobiol. 20: 525-34. PMID: 7898614
7. The neurobiology of canine distemper virus infection.  |  Vandevelde, M. and Zurbriggen, A. 1995. Vet Microbiol. 44: 271-80. PMID: 8588322
8. Canine distemper virus--a morbillivirus in search of new hosts?  |  Harder, TC. and Osterhaus, AD. 1997. Trends Microbiol. 5: 120-4. PMID: 9080611

Monoclonal antibodies for mammalian and non-mammalian protein targets represent essentially all targets covered by polyclonal antibodies. Over 8,300 of our antibodies are offered as ImmunoCruz^® conjugates which eliminates the need for a secondary antibody.

Santa Cruz Biotechnology antibodies have over 360,000 research citations. Anti-CDV envelope antigen Antibody (7515) has 0 citations in a variety of scientific publications.

Primary antibodies for mammalian target proteins are recommended for the detection of a range of mammalian species, primarily of mouse, rat and human species. Many mammalian antibodies are also ideal for veterinary research and reactive with ovine, porcine, caprine, feline, canine, bovine and equine protein targets. Santa Cruz Biotechnology primary monoclonal antibodies are suitable for laboratory research applications and are not intended for diagnostic or therapeutic use.

CDV envelope antigen Antibody (7515) Specifications

Alternate Product Name: CDV envelope antigen

Product Clone Name: 7515

Classification: Primary Antibody

Clonality: Monoclonal Antibody

Antibody Isotype: IgG_2a

Amino Acids:

Epitope Target: CDV envelope antigen

Epitope Species: CDV

Product Reactivity/Detection: envelope antigen

Species Reactivity/Detection: CDV

Additional Mammalian Reactivity: N/A

Additional Non-Mammalian Reactivity: N/A

Applications: ELISA

Vialing Information: Each vial contains 100 µg IgG_2a in 1.0 ml of PBS with < 0.1% sodium azide and 0.1% gelatin

Research Citations: 0 citations in various scientific publications

Available Conjugates/Forms for CDV envelope antigen Antibody (7515): N/A