Cdk7 Antibody (MO-1): sc-56284
- Cdk7 Antibody (MO-1) is a mouse monoclonal IgG2b κ, cited in 8 publications, provided at 200 µg/ml
- raised against the C-terminus of Cdk7 of human origin
- recommended for detection of Cdk7 of mouse, rat and human origin by WB, IP, IF and FCM
- available conjugated to either phycoerythrin or FITC for IF, IHC(P) and FCM
- See Cdk7 (C-4): sc-7344 for Cdk7 antibody conjugates, including AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 and 790.
- m-IgG Fc BP-HRP is the preferred secondary detection reagent for Cdk7 Antibody (MO-1) for WB applications. This reagent is now offered in a bundle with Cdk7 Antibody (MO-1) (see ordering information below).
Cdk7 Antibody (MO-1) is a mouse monoclonal IgG2b antibody that detects Cdk7 in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and flow cytometry (FCM). Cdk7 plays a pivotal role in the regulation of the cell cycle by functioning as a cyclin-dependent kinase-activating kinase (CAK), which is essential for the activation of other cyclin-dependent kinases, including Cdk2 and Cdc2. This activation is crucial for the progression of cells through the cell cycle, as it ensures that the necessary phosphorylation events occur at specific threonine residues, such as Thr 160 in Cdk2 and Thr 161 in Cdc2. Cdk7 is located in the nucleus, where Cdk7 interacts with various cyclins, including cyclin H, which is vital for its activation. Proper functioning of Cdk7 is important not only for cell cycle regulation but also for transcriptional regulation, as Cdk7 phosphorylates the carboxy-terminal domain of RNA polymerase II, thereby facilitating the transcription process. Anti-Cdk7 antibody (MO-1) is an invaluable tool for researchers studying cell cycle dynamics and the intricate signaling pathways that govern cellular proliferation and differentiation.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Cdk7 Antibody (MO-1) | sc-56284 | 200 µg/ml | $322.00 | |||
Cdk7 Antibody (MO-1): m-IgG Fc BP-HRP Bundle | sc-551938 | 200 µg Ab; 10 µg BP | $361.00 | |||
Cdk7 Antibody (MO-1) FITC | sc-56284 FITC | 200 µg/ml | $336.00 | |||
Cdk7 Antibody (MO-1) PE | sc-56284 PE | 200 µg/ml | $349.00 |