Date published: 2025-9-5

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Cdk7 抗体 (MO-1): sc-56284

4.6(8)
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说明书
  • Cdk7抗体(MO-1)是小鼠单克隆IgG2b κ, 在8篇文献中引用,规格为200 µg/ml
  • 针对Cdk7的human起源的C-terminus的
  • 推荐用于 mouse, rat 和 human 来源的Cdk7 WB, IP, IF 和 FCM检测
  • 还可偶联藻红蛋白 以及 FITC 用于IF, IHC(P) 和 FCM
  • 看 Cdk7 (C-4): sc-7344,可查看有标记的 Cdk7 抗体,包括AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 和 790
  • m-IgG Fc BP-HRP是Cdk7 Antibody (MO-1) 适用于 WB 应用。 的首选辅助检测试剂。该试剂现与Cdk7 Antibody (MO-1) 搭配使用(请参阅下面的订购信息)。

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関連項目

细胞周期的进展需要激活一系列被称为细胞周期蛋白依赖性激酶(Cdks)的酶。单体催化亚基Cdk2是启动细胞周期进展的关键酶,但它是完全无活性的。通过结合调节性细胞周期蛋白(如细胞周期蛋白D1)可以实现部分激活,而完全激活则需要在Thr 160上进行额外的磷酸化。负责在Thr 160上磷酸化Cdk2以及在Thr 161上磷酸化Cdc2 p34的酶被称为Cdk激活激酶(CAK),该酶已被部分纯化,并显示由催化亚基和调节亚基组成。催化亚基被命名为Cdk7,已被鉴定为MO15的哺乳动物同源物,MO15是在海星和非洲爪蟾中表现的一种蛋白激酶。调节亚基是一种新型细胞周期蛋白(细胞周期蛋白H),是激活Cdk7所必需的。与其他Cdks一样,Cdk7包含一个保守的苏氨酸残基,该残基对于其完全活性是必需的;该残基的突变会严重降低CAK的活性。

仅限研究使用。不适用于诊断和治疗用途。

订购信息

产品名称产品编号规格价格数量收藏夹

Cdk7 抗体 (MO-1)

sc-56284
200 µg/ml
$316.00

Cdk7 (MO-1): m-IgG Fc BP-HRP 套装

sc-551938
200 µg Ab; 10 µg BP
$354.00

Cdk7 抗体 (MO-1) FITC

sc-56284 FITC
200 µg/ml
$330.00

Cdk7 抗体 (MO-1) PE

sc-56284 PE
200 µg/ml
$343.00

How can Cdk7 (MO-1): sc-56284 mouse monoclonal antibody be used for double or triple staining, if the other primary antibodies are also raised in mouse?

Asked by: Germaine
In this case, we recommend using a directly conjugated mouse monoclonal primary antibody. This antibody is available conjugated to phycoerythrin (sc-56284 PE) or fluoroscein (sc-56284 FITC).
Answered by: Technical Support
Date published: 2017-02-27
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Rated 5 out of 5 by from Goof for WB and IPIt is good for Western blot and IP with human cell nuclear extract.
Date published: 2018-02-04
Rated 5 out of 5 by from Good resultWe use it for IF applications and got good result.
Date published: 2016-12-02
Rated 5 out of 5 by from Good specificityGood specificity, it is suitable for my current experimental study, unexpected results
Date published: 2016-11-23
Rated 5 out of 5 by from Good specificityGood specificity and signal strength for WB in NIH/3T3 and K-562 whole cell lysates. -SCBT QGood specificity and signal strength for WB in NIH/3T3 and K-562 whole cell lysates. -SCBT QCC
Date published: 2016-11-05
Rated 4 out of 5 by from Works well for IF applicationsWorks well for IF applications, positive in HeLa. -SCBT QC
Date published: 2015-04-01
Rated 5 out of 5 by from WB positive with SW480 cellsWB positive with SW480 cells. -SCBT Publication Review
Date published: 2015-02-26
Rated 4 out of 5 by from Worked with transfected lysate by WBWorked with transfected lysate by WB -SCBT QC
Date published: 2015-02-05
Rated 4 out of 5 by from Good specificity and signal strength forGood specificity and signal strength for WB in NIH/3T3 and K-562 whole cell lysates. -SCBT QC
Date published: 2014-07-16
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Cdk7 抗体 (MO-1) is rated 4.6 out of 5 by 8.
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