CD30L Antibody (RM153): sc-19984
- CD30L Antibody (RM153) is a rat monoclonal IgG2b CD30L antibody, cited in 1 publications, provided at 200 µg/ml
- CD30L Antibody (RM153) is recommended for detection of CD30L of mouse origin by WB, IP, IF and FCM
- CD30L Antibody (RM153) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also provided azide-free for blocking of mouse CD30 binding to CD30L, sc-19984 L, 200 µg/0.1 ml
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for CD30L Antibody (RM153). This work is in progress.
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CD30L Antibody (RM153) is a rat monoclonal IgG2b antibody that detects CD30L protein of mouse origin by immunofluorescence (IF) and flow cytometry (FCM). Anti-CD30L antibody (RM153) is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates, providing versatility for different experimental needs. CD30L protein plays a crucial role in immune regulation, acting as a ligand for CD30 receptor, which is part of the tumor necrosis factor receptor superfamily. This interaction is vital for mediating co-stimulatory signals that enhance T cell activation and proliferation, particularly in the context of immune responses to tumors and infections. CD30L′s importance is underscored by involvement in various hematologic malignancies, including Hodgkin′s lymphoma, where CD30L can influence the behavior of neoplastic cells. Additionally, CD30L has been shown to enhance proliferation of Hodgkin′s cell line HDLM-2, while exerting antiproliferative effects on large cell anaplastic lymphoma cell lines, highlighting CD30L′s dual role in tumor biology. CD30L′s ability to modulate immune responses makes anti-CD30L antibody (RM153) a valuable tool for researchers studying immune interactions and cancer biology.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
CD30L Antibody (RM153) References:
- CD30 ligand signal transduction involves activation of a tyrosine kinase and of mitogen-activated protein kinase in a Hodgkin's lymphoma cell line. | Wendtner, CM., et al. 1995. Cancer Res. 55: 4157-61. PMID: 7545087
- Tumor necrosis factor ligand superfamily: involvement in the pathology of malignant lymphomas. | Gruss, HJ. and Dower, SK. 1995. Blood. 85: 3378-404. PMID: 7780126
- Tumor necrosis factor receptor superfamily members and their ligands. | Armitage, RJ. 1994. Curr Opin Immunol. 6: 407-13. PMID: 7917108
- CD27: marker and mediator of T-cell activation? | Hintzen, RQ., et al. 1994. Immunol Today. 15: 307-11. PMID: 8086099
- CD30 antigen, a marker for Hodgkin's lymphoma, is a receptor whose ligand defines an emerging family of cytokines with homology to TNF. | Smith, CA., et al. 1993. Cell. 73: 1349-60. PMID: 8391931
- Structure and expression of murine CD30 and its role in cytokine production. | Bowen, MA., et al. 1996. J Immunol. 156: 442-9. PMID: 8543792
- CD27-CD70 interaction: unravelling its implication in normal and neoplastic B-cell growth. | Lens, SM., et al. 1995. Leuk Lymphoma. 18: 51-9. PMID: 8580829
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
CD30L Antibody (RM153) | sc-19984 | 200 µg/ml | $322.00 | |||
CD30L Antibody (RM153) L | sc-19984 L | 200 µg/0.1 ml | $322.00 | |||
CD30L Antibody (RM153) AC | sc-19984 AC | 500 µg/ml, 25% agarose | $424.00 | |||
CD30L Antibody (RM153) HRP | sc-19984 HRP | 200 µg/ml | $322.00 | |||
CD30L Antibody (RM153) FITC | sc-19984 FITC | 200 µg/ml | $336.00 | |||
CD30L Antibody (RM153) PE | sc-19984 PE | 200 µg/ml | $349.00 | |||
CD30L Antibody (RM153) Alexa Fluor® 488 | sc-19984 AF488 | 200 µg/ml | $364.00 | |||
CD30L Antibody (RM153) Alexa Fluor® 546 | sc-19984 AF546 | 200 µg/ml | $364.00 | |||
CD30L Antibody (RM153) Alexa Fluor® 594 | sc-19984 AF594 | 200 µg/ml | $364.00 | |||
CD30L Antibody (RM153) Alexa Fluor® 647 | sc-19984 AF647 | 200 µg/ml | $364.00 | |||
CD30L Antibody (RM153) Alexa Fluor® 680 | sc-19984 AF680 | 200 µg/ml | $364.00 | |||
CD30L Antibody (RM153) Alexa Fluor® 790 | sc-19984 AF790 | 200 µg/ml | $364.00 |