CCDC180 Antibody (G-10): sc-398312

CCDC180 Antibody (G-10) is a mouse monoclonal IgM antibody that detects CCDC180 of mouse, rat, and human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). Anti-CCDC180 antibody (G-10) is available as the non-conjugated form. CCDC180 is located in the cytoplasm and plays a crucial role in cellular processes such as cell division and differentiation. Proper localization of CCDC180 is essential for maintaining cellular integrity and function, as mislocalization can lead to various developmental disorders and diseases. CCDC180′s interaction with other cytoplasmic components is vital for signaling pathways that regulate cell growth and apoptosis, highlighting CCDC180′s importance in both normal physiology and disease states. Chromosome 9, where CCDC180 is located, is significant not only for its role in gender determination but also for its association with various genetic disorders, including hereditary hemorrhagic telangiectasia and familial dysautonomia. CCDC180 monoclonal antibody (G-10) provides a valuable tool for researchers studying these critical biological processes and their implications in health and disease.

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CCDC180 Antibody (G-10) References:

1. DNA sequence and analysis of human chromosome 9.  |  Humphray, SJ., et al. 2004. Nature. 429: 369-74. PMID: 15164053
2. BCR-ABL activates STAT3 via JAK and MEK pathways in human cells.  |  Coppo, P., et al. 2006. Br J Haematol. 134: 171-9. PMID: 16846476
3. BCR and its mutants, the reciprocal t(9;22)-associated ABL/BCR fusion proteins, differentially regulate the cytoskeleton and cell motility.  |  Zheng, X., et al. 2006. BMC Cancer. 6: 262. PMID: 17090304
4. Gene expression fingerprinting for human hereditary hemorrhagic telangiectasia.  |  Fernandez-L, A., et al. 2007. Hum Mol Genet. 16: 1515-33. PMID: 17420163
5. Phenotypic and cytogenetic spectrum of 9p trisomy.  |  Temtamy, SA., et al. 2007. Genet Couns. 18: 29-48. PMID: 17515299
6. Potential role of tubulin acetylation and microtubule-based protein trafficking in familial dysautonomia.  |  Gardiner, J., et al. 2007. Traffic. 8: 1145-9. PMID: 17605759
7. Pulmonary vascular manifestations of hereditary hemorrhagic telangiectasia (rendu-osler disease).  |  Cottin, V., et al. 2007. Respiration. 74: 361-78. PMID: 17641482
8. A humanized IKBKAP transgenic mouse models a tissue-specific human splicing defect.  |  Hims, MM., et al. 2007. Genomics. 90: 389-96. PMID: 17644305
9. Atypical BCR-ABL mRNA transcripts in adult acute lymphoblastic leukemia.  |  Burmeister, T., et al. 2007. Haematologica. 92: 1699-702. PMID: 18055996
10. Genomic variations in paired normal controls for lung adenocarcinomas.  |  Qu, LW., et al. 2017. Oncotarget. 8: 104113-104122. PMID: 29262625
11. Identification of Coiled-Coil Domain-Containing Protein 180 and Leucine-Rich Repeat-Containing Protein 4 as Potential Immunohistochemical Markers for Liposarcoma Based on Proteomic Analysis Using Formalin-Fixed, Paraffin-Embedded Tissue.  |  Aoyama, T., et al. 2019. Am J Pathol. 189: 1015-1028. PMID: 30790560
12. Genome-wide linkage analysis combined with genome sequencing in large families with intracranial aneurysms.  |  Bakker, MK., et al. 2022. Eur J Hum Genet. 30: 833-840. PMID: 35228681

Monoclonal antibodies for mammalian and non-mammalian protein targets represent essentially all targets covered by polyclonal antibodies. Over 8,300 of our antibodies are offered as ImmunoCruz^® conjugates which eliminates the need for a secondary antibody.

Santa Cruz Biotechnology antibodies have over 360,000 research citations. Anti-CCDC180 Antibody (G-10) has 0 citations in a variety of scientific publications.

Primary antibodies like Anti-CCDC180 Antibody (G-10) for mammalian target proteins are recommended for the detection of a range of mammalian species, primarily of mouse, rat and human species. Many mammalian antibodies are also ideal for veterinary research and reactive with ovine, porcine, caprine, feline, canine, bovine and equine protein targets. Santa Cruz Biotechnology primary monoclonal antibodies are suitable for laboratory research applications and are not intended for diagnostic or therapeutic use.

CCDC180 Antibody (G-10) Specifications

Alternate Product Name: CCDC180

Product Clone Name: G-10

Classification: Primary Antibody

Clonality: Monoclonal Antibody

Antibody Isotype: IgM kappa light chain

Amino Acids: 1-32

Epitope Target: Ccdc180

Epitope Species: mouse

Product Reactivity/Detection: CCDC180

Species Reactivity/Detection: mouse, rat, human

Additional Mammalian Reactivity: N/A

Additional Non-Mammalian Reactivity: N/A

Applications: WB, IP, IF, ELISA

Vialing Information: Each vial contains 200 µg IgM kappa light chain in 1.0 ml of PBS with < 0.1% sodium azide and 0.1% gelatin

Research Citations: 0 citations in various scientific publications

Available Conjugates/Forms for CCDC180 Antibody (G-10): P: Blocking Peptide