cathepsin D Antibody (E-7): sc-13148
- cathepsin D Antibody (E-7) is a mouse monoclonal IgG1 κ, cited in 19 publications, provided at 200 µg/ml
- raised against amino acids 1-75 of cathepsin D of human origin
- cathepsin D Antibody (E-7) is recommended for detection of cathepsin D of human origin by WB, IP, IF, IHC(P), FCM and ELISA
- Anti-cathepsin D Antibody (E-7) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- m-IgG1 BP-HRP is the preferred secondary detection reagent for cathepsin D Antibody (E-7) for WB and IHC(P) applications. This reagent is now offered in a bundle with cathepsin D Antibody (E-7) (see ordering information below).
QUICK LINKS
SEE ALSO...
cathepsin D Antibody (E-7) is a mouse monoclonal IgG1 kappa light chain antibody raised against amino acids 1-75 of human cathepsin D, with validated applications including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), flow cytometry (FCM), and enzyme-linked immunosorbent assay (ELISA). Cathepsin D, also known as CTSD, is a lysosomal aspartyl protease involved in protein degradation and peptide processing. anti-cathepsin D antibody (E-7) plays a crucial role in studying cellular metabolism, autophagy, and apoptosis by detecting proteins broken down into smaller peptides within the acidic lysosomal environment. This enzyme is synthesized as an inactive precursor and activated through proteolytic cleavage, which is essential for enzymatic activity. Cathepsin D also cleaves specific protein precursors to release regulatory peptides that modulate various cellular processes. Enzymatic activity is tightly regulated, as dysregulation has been implicated in pathological conditions, including cancer, where cathepsin D may promote tumor progression and metastasis. The cathepsin D gene is regulated by multiple transcription factors, including Sp1 and AP-2, which control expression in response to cellular and environmental signals. cathepsin D monoclonal antibody (E-7) is an invaluable tool for investigating functional and regulatory mechanisms in health and disease.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
cathepsin D Antibody (E-7) | sc-13148 | 200 µg/ml | $316.00 | |||
cathepsin D Antibody (E-7): m-IgG1 BP-HRP Bundle | sc-551909 | 200 µg Ab; 20 µg BP | $354.00 | |||
cathepsin D Antibody (E-7) AC | sc-13148 AC | 500 µg/ml, 25% agarose | $416.00 | |||
cathepsin D Antibody (E-7) HRP | sc-13148 HRP | 200 µg/ml | $316.00 | |||
cathepsin D Antibody (E-7) FITC | sc-13148 FITC | 200 µg/ml | $330.00 | |||
cathepsin D Antibody (E-7) PE | sc-13148 PE | 200 µg/ml | $343.00 | |||
cathepsin D Antibody (E-7) Alexa Fluor® 488 | sc-13148 AF488 | 200 µg/ml | $357.00 | |||
cathepsin D Antibody (E-7) Alexa Fluor® 546 | sc-13148 AF546 | 200 µg/ml | $357.00 | |||
cathepsin D Antibody (E-7) Alexa Fluor® 594 | sc-13148 AF594 | 200 µg/ml | $357.00 | |||
cathepsin D Antibody (E-7) Alexa Fluor® 647 | sc-13148 AF647 | 200 µg/ml | $357.00 | |||
cathepsin D Antibody (E-7) Alexa Fluor® 680 | sc-13148 AF680 | 200 µg/ml | $357.00 | |||
cathepsin D Antibody (E-7) Alexa Fluor® 790 | sc-13148 AF790 | 200 µg/ml | $357.00 |