Carvedilol N′-Carbamate β-D-Glucopyranuronic Acid (CAS 216973-68-1)

Carvedilol N′-Carbamate β-D-Glucopyranuronic Acid is a chemically modified derivative of carvedilol, specifically designed for research into the biochemical and environmental fate of this molecule. This derivative incorporates a β-D-glucopyranuronic acid, a form of glucuronic acid, which is pivotal in the study of glucuronidation, a major metabolic pathway that enhances the solubility of compounds for more efficient excretion. The carbamate group in the structure further introduces an aspect of chemical stability and reactivity, making it a valuable molecule for studying enzyme interactions, particularly with UDP-glucuronosyltransferase, which facilitates the conjugation of glucuronic acid to various substances. This process is crucial for understanding the biotransformation mechanisms that affect the environmental persistence and biological activity of synthetic compounds. In non-clinical research settings, Carvedilol N′-Carbamate β-D-Glucopyranuronic Acid helps explain how modifications in chemical structure can impact metabolic pathways, offering insights into the design of environmentally benign compounds and the development of models for predicting the behavior of similar substances in biological systems. This knowledge is instrumental for regulatory science and environmental safety assessments, contributing to strategies for minimizing ecological disruption while enhancing the understanding of compound behavior in natural and experimental settings.