Date published: 2025-12-5

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Carbenicillin disodium salt (CAS 4800-94-6)

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Alternate Names:
Carbenicillin disodium salt is also known as α-Carboxybenzylpenicillin disodium salt.
Application:
Carbenicillin disodium salt is a β-lactam antibiotic
CAS Number:
4800-94-6
Purity:
≥90%
Molecular Weight:
422.36
Molecular Formula:
C17H16N2O6S•2Na
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Carbenicillin disodium salt is a penicillin-derived, beta-lactam antibiotic which inhibits the synthesis of peptidoglycan, a key component of the bacterial cell wall. In studies investigating the roles of biogenic polyamines, spermidine and spermine, on antibiotic susceptibility of several microorganisms it was observed that the mean inhibitory concentration (MIC) of beta-lactam antibiotics such as Carbenicillin was decreased with the addition of spermidine and spermine to cultures of Escherichia coli and Salmonella enterica. Additionally, in plants Carbenicillin was investigated for its effects on morphology and growth of Beta vulgaris, Capsicum annuum and Glehnia littoralis roots. In this study, Carbenicillin was noted to inhibit root elongation while promoting root branching in contrast to Ampicillin (sc-202951).


Carbenicillin disodium salt (CAS 4800-94-6) References

  1. New carbenicillin-hydrolyzing beta-lactamase (CARB-7) from Vibrio cholerae non-O1, non-O139 strains encoded by the VCR region of the V. cholerae genome.  |  Melano, R., et al. 2002. Antimicrob Agents Chemother. 46: 2162-8. PMID: 12069969
  2. Arbuscular mycorrhizal fungi influence water relations, gas exchange, abscisic acid and growth of micropropagated chile ancho pepper (Capsicum annuum) plantlets during acclimatization and post-acclimatization.  |  Estrada-Luna, AA. and Davies, FT. 2003. J Plant Physiol. 160: 1073-83. PMID: 14593809
  3. Penicillin derivatives induce chemical structure-dependent root development, and application for plant transformation.  |  ur Rahman, L., et al. 2004. Plant Cell Rep. 22: 668-77. PMID: 14727052
  4. Probiotic bifidobacteria protect mice from lethal infection with Shiga toxin-producing Escherichia coli O157:H7.  |  Asahara, T., et al. 2004. Infect Immun. 72: 2240-7. PMID: 15039348
  5. Tolerance to antimicrobial agents and persistence of Escherichia coli and cyanobacteria.  |  Samuilov, VD., et al. 2008. Biochemistry (Mosc). 73: 833-8. PMID: 18707592
  6. Polyamines can increase resistance of Neisseria gonorrhoeae to mediators of the innate human host defense.  |  Goytia, M. and Shafer, WM. 2010. Infect Immun. 78: 3187-95. PMID: 20439477
  7. A comparison study of Agrobacterium-mediated transformation methods for root-specific promoter analysis in soybean.  |  Li, C., et al. 2014. Plant Cell Rep. 33: 1921-32. PMID: 25097075
  8. Production of Herbicide-Sensitive Strain to Prevent Volunteer Rice Infestation Using a CRISPR-Cas9 Cytidine Deaminase Fusion.  |  Komatsu, A., et al. 2020. Front Plant Sci. 11: 925. PMID: 32849670
  9. Short-chain reactive probes as tools to unravel the Pseudomonas aeruginosa quorum sensing regulon.  |  Yashkin, A., et al. 2021. Chem Sci. 12: 4570-4581. PMID: 34163722
  10. Assembly of plant virus agroinfectious clones using biological material or DNA synthesis.  |  Pasin, F. 2022. STAR Protoc. 3: 101716. PMID: 36149792
  11. Identification of genes for seed isoflavones based on bulk segregant analysis sequencing in soybean natural population.  |  Azam, M., et al. 2023. Theor Appl Genet. 136: 13. PMID: 36662254
  12. Carbenicillin: chemistry and mode of action.  |  Butler, K., et al. 1970. J Infect Dis. 122: Suppl:S1-8. PMID: 4248289
  13. Stereoselective renal tubular secretion of carbenicillin.  |  Itoh, T., et al. 1993. Antimicrob Agents Chemother. 37: 2327-32. PMID: 8285614
  14. Determination of ticarcillin epimers in plasma and urine with high-performance liquid chromatography.  |  Li, YH., et al. 1997. J Chromatogr B Biomed Sci Appl. 694: 145-52. PMID: 9234857
  15. Hollow-fire bioreactors compared to batch and chemostat culture for the production of a recombinant toxoid by a marine Iibrio.  |  Lloyd, JR., et al. 1997. Appl Microbiol Biotechnol. 48: 155-61. PMID: 9299772

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Carbenicillin disodium salt, 250 mg

sc-202519
250 mg
$45.00

Carbenicillin disodium salt, 1 g

sc-202519A
1 g
$129.00

Carbenicillin disodium salt, 5 g

sc-202519B
5 g
$306.00