Calgranulin C Antibody (19F5): sc-101347
- Calgranulin C Antibody (19F5) is a mouse monoclonal IgG1 Calgranulin C antibody, cited in 5 publications, provided at 50 µg/0.5 ml
- raised against Calgranulin C of human origin
- recommended for detection of Calgranulin C of human origin by WB, IF and IHC(P)
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for Calgranulin C Antibody (19F5). This work is in progress.
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Calgranulin C Antibody (19F5) is a mouse monoclonal IgG1 antibody that detects the Calgranulin C protein of human origin by western blotting (WB), immunofluorescence (IF), and immunohistochemistry with paraffin-embedded sections (IHCP). Anti-Calgranulin C antibody (19F5) is available as a non-conjugated format and belongs to the EF-hand type calcium-binding protein family, which includes other notable members such as calbindin and S100 proteins. Calgranulin C, also known as S100A12, plays a crucial role in immune response, particularly in the activation and recruitment of immune cells during inflammation. S100A12 is primarily expressed in macrophages and epithelial cells, where S100A12 acts as a pro-inflammatory mediator, influencing the behavior of various immune cells and contributing to the pathophysiology of several inflammatory diseases. The ability of S100A12 to interact with specific proteins, such as receptor for advanced glycation end products (RAGE), underscores its importance in cellular signaling pathways that regulate inflammation and tissue repair. Using anti-Calgranulin C antibody (19F5) in research can provide valuable insights into the mechanisms of immune response and the role of S100A12 in various pathological conditions.
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Calgranulin C Antibody (19F5) References:
- The heterodimeric complex of MRP-8 (S100A8) and MRP-14 (S100A9). Antibody recognition, epitope definition and the implications for structure. | Hessian, PA. and Fisher, L. 2001. Eur J Biochem. 268: 353-63. PMID: 11168370
- Isolation of a rat S100 alpha cDNA and distribution of its mRNA in rat tissues. | Zimmer, DB., et al. 1991. Brain Res Bull. 27: 157-62. PMID: 1742602
- Calcium-binding proteins of the EF-type. | Heizmann, CW. 1988. J Cardiovasc Pharmacol. 12 Suppl 5: S30-7. PMID: 2469875
- Monoclonal antibody 5.5 reacts with p8,14, a myeloid molecule associated with some vascular endothelium. | Hogg, N., et al. 1989. Eur J Immunol. 19: 1053-61. PMID: 2666142
- Developmental and functional studies of parvalbumin and calbindin D28K in hypothalamic neurons grown in serum-free medium. | Pfyffer, GE., et al. 1987. J Neurochem. 49: 442-51. PMID: 3298546
- Developmental appearance of the Ca2+-binding proteins parvalbumin, calbindin D-28K, S-100 proteins and calmodulin during testicular development in the rat. | Kägi, U., et al. 1988. Cell Tissue Res. 252: 359-65. PMID: 3383215
- Increase of skeletal muscle relaxation speed by direct injection of parvalbumin cDNA. | Müntener, M., et al. 1995. Proc Natl Acad Sci U S A. 92: 6504-8. PMID: 7604022
- S100 protein expression in subpopulations of neurons of rat brain. | Rickmann, M. and Wolff, JR. 1995. Neuroscience. 67: 977-91. PMID: 7675218
- Retinoic acid regulates the expression of the calcium binding protein, calbindin-D28K. | Wang, YZ. and Christakos, S. 1995. Mol Endocrinol. 9: 1510-21. PMID: 8584029
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Calgranulin C Antibody (19F5) | sc-101347 | 50 µg/0.5 ml | $339.00 |